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  1. 学術雑誌論文

Chemical characterization of oligosaccharides in the milk of six species of New and Old world monkeys

https://obihiro.repo.nii.ac.jp/records/731
https://obihiro.repo.nii.ac.jp/records/731
a8cf93c3-bd92-457e-8a06-61bd01ac95a9
名前 / ファイル ライセンス アクション
GLYC594.pdf GLYC594.pdf (706.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2012-03-19
タイトル
言語 en
タイトル Chemical characterization of oligosaccharides in the milk of six species of New and Old world monkeys
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 old world monkey
キーワード
言語 en
主題Scheme Other
主題 new world monkey
キーワード
言語 en
主題Scheme Other
主題 milk oligosaccharide
キーワード
言語 en
主題Scheme Other
主題 rhesus macaque
キーワード
言語 en
主題Scheme Other
主題 toque macaque
キーワード
言語 en
主題Scheme Other
主題 baboon
キーワード
言語 en
主題Scheme Other
主題 capuchin
キーワード
言語 en
主題Scheme Other
主題 mantled howler
キーワード
言語 en
主題Scheme Other
主題 squirrel monkey
キーワード
言語 en
主題Scheme Other
主題 N-glycolylneuraminic acid
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Goto, Kohta

× Goto, Kohta

WEKO 1562

en Goto, Kohta

Search repository
福田, 健二

× 福田, 健二

WEKO 17
CiNii ID 9000001960660
e-Rad 80419217

en Fukuda, Kenji

ja 福田, 健二
ISNI

Search repository
Senda, Akitsugu

× Senda, Akitsugu

WEKO 1563

en Senda, Akitsugu

Search repository
Saito, Tadao

× Saito, Tadao

WEKO 331
CiNii ID 9000003495007
e-Rad 80419217

en Saito, Tadao

Search repository
Kimura, Kazumasa

× Kimura, Kazumasa

WEKO 1564

en Kimura, Kazumasa

Search repository
Glander, Kenneth E.

× Glander, Kenneth E.

WEKO 1565

en Glander, Kenneth E.

Search repository
Hinde, Katie

× Hinde, Katie

WEKO 1566

en Hinde, Katie

Search repository
Dittus, Wolfgang

× Dittus, Wolfgang

WEKO 1567

en Dittus, Wolfgang

Search repository
Milligan, Lauren A.

× Milligan, Lauren A.

WEKO 1568

en Milligan, Lauren A.

Search repository
Power, Michael L.

× Power, Michael L.

WEKO 1569

en Power, Michael L.

Search repository
Oftedal, Olav T.

× Oftedal, Olav T.

WEKO 1570

en Oftedal, Olav T.

Search repository
浦島, 匡

× 浦島, 匡

WEKO 291
CiNii ID 1000080185082
e-Rad 80185082
researchmap read0167539

en Urashima, Tadasu

ja 浦島, 匡
ISNI

Search repository
抄録
内容記述タイプ Abstract
内容記述 Human and great ape milks contain a diverse array of milk oligosaccharides, but little is known about the milk oligosaccharides of other primates, and how they differ among taxa. Neutral and acidic oligosaccharides were isolated from the milk of three species of Old World or catarrhine monkeys (Cercopithecidae: rhesus macaque (Macaca mulatta), toque macaque (Macaca sinica) and Hamadryas baboon (Papio hamadryas)) and three of New World or platyrrhine monkeys (Cebidae: tufted capuchin (Cebus apella)and Bolivian squirrel monkey (Saimiri boliviensis); Atelidae: mantled howler (Alouatta palliata)). The milks of these species contained 6-8% total sugar, most of which was lactose: the estimated ratio of oligosaccharides to lactose in Old World monkeys (1:4 to 1:6) was greater than in New World monkeys (1:12 to 1:23). The chemical structures of the oligosaccharides were determined mainly by 1H-NMR spectroscopy. Oligosaccharides containing the type II unit (Gal(β1-4)GlcNAc) were found in the milk of the rhesus macaque, toque macaque, Hamadryas baboon and tufted capuchin, but oligosaccharides containing the type I unit (Gal(β1-3)GlcNAc), which have been found in human and many great ape milks, were absent from the milk of all species studied. Oligosaccharides containing Lewis x (Gal(β1-4)[Fuc(α1-3)]GlcNAc) and 3-fucosyl lactose (Gal(β1-4)[Fuc(α1-3)]Glc) were found in the milk of the three cercopithecid monkey species, while 2-fucosyl lactose (Fuc(α1-2)Gal(β1-4)Glc) was absent from all species studied. All of these milks contained acidic oligosaccharides that had N-acetylneuraminic acid as part of their structures, but did not contain oligosaccharides that had N-glycolylneuraminic acid, in contrast to the milk or colostrum of great apes which contain both types of acidic oligosaccharides. Two GalNAc-containing oligosaccharides, lactose 3’-O-sulfate and lacto-N-novopentaose I (Gal(β1-3)[Gal(β1-4)GlcNAc(β1-6)]Gal(β1-4)Glc) were found only in the milk of rhesus macaque, hamadryas baboon and tufted capuchin, respectively. Further research is needed to determine the extent to which the milk oligosaccharide patterns observed among these taxa represent wider phylogenetic trends among primates and how much variation occurs among individuals or species.
言語 en
書誌情報 en : Glycoconjugate Journal

巻 27, p. 703-715, 発行日 2010
出版者
言語 en
出版者 Springer
ISSN
収録物識別子タイプ PISSN
収録物識別子 02820080
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10451191
権利
言語 en
権利情報 Springer
フォーマット
内容記述タイプ Other
内容記述 application/pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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