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Sialyl Oligosaccharides in the Milk of Japanese Women: Changes in Concentration during the Course of Lactation
https://obihiro.repo.nii.ac.jp/records/230
https://obihiro.repo.nii.ac.jp/records/23024f0cb3d-1e42-4f90-bce8-30220023055c
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2012-07-11 | |||||||||
タイトル | ||||||||||
言語 | en | |||||||||
タイトル | Sialyl Oligosaccharides in the Milk of Japanese Women: Changes in Concentration during the Course of Lactation | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | human milk | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | sialyl oligosaccharide | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | lactation period | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | PMP | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | reverse phase HPLC | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
その他(別言語等)のタイトル | ||||||||||
その他のタイトル | 日本人女性の乳中に含まれるシアリルオリゴ糖の泌乳期における経時的変動 | |||||||||
言語 | ja | |||||||||
著者 |
Sumiyoshi, Wataru
× Sumiyoshi, Wataru× 浦島, 匡
WEKO
291
× Nakamura, Tadashi× 荒井, 威吉× Nagasawa, Takashi× Saito, Tadao× Tsumura, Norihiko× Wang, Bing× Brand-Miller, Janette× Watanabe, Yoko× Kimura, Kazumasa |
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | The concentrations of the six major sialyl oligosaccharides found in the milk of 24 Japanese women were determined using reverse phase high performance liquid chromatography of the 3-methyl-1-phenyl-5- pyrazolone derivatives of the oligosaccharides. The milk was collected at 4, 10, 30 and 100 days postpartum. The concentrations of all six oligosaccharides decreased during the course of lactation. The concentrations of 6'-sialyllactose, sialyllacto-N-tetraose b and disialyllacto-N-tetraose decreased only after 10 days postpartum, whereas those of sialyllacto-N-tetraose a and sialyllacto-N-neotetraose c as well as 3'-sialyllactose decreased from 4 days postpartum. Large differences were observed between present data and those previously reported for Italian women, both in terms of the content and in the variation pattern of each oligosaccharide during the course of lactation. These differences may be caused by the different ethnicity of the donors as well as the assay methods used in the studies. | |||||||||
言語 | en | |||||||||
抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | 日本人女性の乳中に含まれる6種のシアリルオリゴ糖濃度の泌乳期に伴う変動を,PMP誘導体化を用いた逆相HPLCにより定量した.DSLNT,6ノーSLおよびLSTb濃度は出産後10日目までの変化は少なく,それ以降減少したが,LSTc,LSTaおよび3'-SL濃度は出産後4日目から100日目まで減少し続けた.本研究と以前に報告されたイタリア人女性の乳でのデータでは,泌乳期の経過に伴う各オリゴ糖の濃度およびその変動パターンに大きな差が見られた.これらの差はドナーの人種差によるばかりではなく,両者の定量方法の違いによっても生じたものと考えられる.また,本研究と以前に報告された日本人女性の乳中における3'-SLおよび6'-SLの定量データとは,泌乳期による変動パターンが類似していた. | |||||||||
言語 | ja | |||||||||
書誌情報 |
en : Journal of Applied Glycoscience 巻 50, 号 4, p. 461-467, 発行日 2003 |
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出版者 | ||||||||||
言語 | en | |||||||||
出版者 | Japanese Society of Applied Glycoscience | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 13447882 | |||||||||
書誌レコードID | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA11809133 | |||||||||
DOI | ||||||||||
関連タイプ | isIdenticalTo | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | info:doi/10.5458/jag.50.461 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | Japanese Society of Applied Glycoscience | |||||||||
フォーマット | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
著者版フラグ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |