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The milk was collected at 4, 10, 30 and 100 days postpartum. The concentrations of all six oligosaccharides decreased during the course of lactation. The concentrations of 6\u0027-sialyllactose, sialyllacto-N-tetraose b and disialyllacto-N-tetraose decreased only after 10 days postpartum, whereas those of sialyllacto-N-tetraose a and sialyllacto-N-neotetraose c as well as 3\u0027-sialyllactose decreased from 4 days postpartum. Large differences were observed between present data and those previously reported for Italian women, both in terms of the content and in the variation pattern of each oligosaccharide during the course of lactation. These differences may be caused by the different ethnicity of the donors as well as the assay methods used in the studies. 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  1. 学術雑誌論文

Sialyl Oligosaccharides in the Milk of Japanese Women: Changes in Concentration during the Course of Lactation

https://obihiro.repo.nii.ac.jp/records/230
https://obihiro.repo.nii.ac.jp/records/230
24f0cb3d-1e42-4f90-bce8-30220023055c
名前 / ファイル ライセンス アクション
Sialyl.pdf Sialyl.pdf (1.4 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2012-07-11
タイトル
言語 en
タイトル Sialyl Oligosaccharides in the Milk of Japanese Women: Changes in Concentration during the Course of Lactation
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 human milk
キーワード
言語 en
主題Scheme Other
主題 sialyl oligosaccharide
キーワード
言語 en
主題Scheme Other
主題 lactation period
キーワード
言語 en
主題Scheme Other
主題 PMP
キーワード
言語 en
主題Scheme Other
主題 reverse phase HPLC
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
その他(別言語等)のタイトル
その他のタイトル 日本人女性の乳中に含まれるシアリルオリゴ糖の泌乳期における経時的変動
言語 ja
著者 Sumiyoshi, Wataru

× Sumiyoshi, Wataru

WEKO 672

en Sumiyoshi, Wataru

Search repository
浦島, 匡

× 浦島, 匡

WEKO 291
CiNii ID 1000080185082
e-Rad 80185082
researchmap read0167539

en Urashima, Tadasu

ja 浦島, 匡
ISNI

Search repository
Nakamura, Tadashi

× Nakamura, Tadashi

WEKO 168
CiNii ID 1000070271749
e-Rad 70271749

en Nakamura, Tadashi

Search repository
荒井, 威吉

× 荒井, 威吉

WEKO 4
CiNii ID 9000007897593

en Arai, Ikichi

ja 荒井, 威吉
ISNI

Search repository
Nagasawa, Takashi

× Nagasawa, Takashi

WEKO 673

en Nagasawa, Takashi

Search repository
Saito, Tadao

× Saito, Tadao

WEKO 331
CiNii ID 9000003495007
e-Rad 80419217

en Saito, Tadao

Search repository
Tsumura, Norihiko

× Tsumura, Norihiko

WEKO 674

en Tsumura, Norihiko

Search repository
Wang, Bing

× Wang, Bing

WEKO 675

en Wang, Bing

Search repository
Brand-Miller, Janette

× Brand-Miller, Janette

WEKO 676

en Brand-Miller, Janette

Search repository
Watanabe, Yoko

× Watanabe, Yoko

WEKO 677

en Watanabe, Yoko

Search repository
Kimura, Kazumasa

× Kimura, Kazumasa

WEKO 678

en Kimura, Kazumasa

Search repository
抄録
内容記述タイプ Abstract
内容記述 The concentrations of the six major sialyl oligosaccharides found in the milk of 24 Japanese women were determined using reverse phase high performance liquid chromatography of the 3-methyl-1-phenyl-5- pyrazolone derivatives of the oligosaccharides. The milk was collected at 4, 10, 30 and 100 days postpartum. The concentrations of all six oligosaccharides decreased during the course of lactation. The concentrations of 6'-sialyllactose, sialyllacto-N-tetraose b and disialyllacto-N-tetraose decreased only after 10 days postpartum, whereas those of sialyllacto-N-tetraose a and sialyllacto-N-neotetraose c as well as 3'-sialyllactose decreased from 4 days postpartum. Large differences were observed between present data and those previously reported for Italian women, both in terms of the content and in the variation pattern of each oligosaccharide during the course of lactation. These differences may be caused by the different ethnicity of the donors as well as the assay methods used in the studies.
言語 en
抄録
内容記述タイプ Abstract
内容記述 日本人女性の乳中に含まれる6種のシアリルオリゴ糖濃度の泌乳期に伴う変動を,PMP誘導体化を用いた逆相HPLCにより定量した.DSLNT,6ノーSLおよびLSTb濃度は出産後10日目までの変化は少なく,それ以降減少したが,LSTc,LSTaおよび3'-SL濃度は出産後4日目から100日目まで減少し続けた.本研究と以前に報告されたイタリア人女性の乳でのデータでは,泌乳期の経過に伴う各オリゴ糖の濃度およびその変動パターンに大きな差が見られた.これらの差はドナーの人種差によるばかりではなく,両者の定量方法の違いによっても生じたものと考えられる.また,本研究と以前に報告された日本人女性の乳中における3'-SLおよび6'-SLの定量データとは,泌乳期による変動パターンが類似していた.
言語 ja
書誌情報 en : Journal of Applied Glycoscience

巻 50, 号 4, p. 461-467, 発行日 2003
出版者
言語 en
出版者 Japanese Society of Applied Glycoscience
ISSN
収録物識別子タイプ PISSN
収録物識別子 13447882
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11809133
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 info:doi/10.5458/jag.50.461
権利
言語 en
権利情報 Japanese Society of Applied Glycoscience
フォーマット
内容記述タイプ Other
内容記述 application/pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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