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Active Immunization Against 5α-androstane-3α, 17β-diol Increases Ovulation Rate in Merino Ewes
https://obihiro.repo.nii.ac.jp/records/171
https://obihiro.repo.nii.ac.jp/records/171e0683590-de08-4b6a-a566-ecc99d6e0299
名前 / ファイル | ライセンス | アクション |
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active.pdf (665.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2011-07-29 | |||||||||
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タイトル | Active Immunization Against 5α-androstane-3α, 17β-diol Increases Ovulation Rate in Merino Ewes | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Ovulation rate | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Sheep | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Immunization | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | 5a-reduced androgen | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
手塚, 雅文
× 手塚, 雅文
WEKO
278
× Nancarrow, Colin. D. |
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | Cyclic Merino ewes were immunized three times against 5α−androstane-3α,17β-diol (3α-diol) at three week intervals (weeks 0,3 and 6). After the third immunization, estrous cycles were synchronized by a series of PG injections and intensive blood samples were obtained for gonadotropin analyses during the mid-luteal phase and during the early follicular phase. Ovulation rates were determined after each immunization and subsequent cloprostenol (PG)-induced luteolysis (weeks 3, 6, 8 and 11). After the second immunization, daily blood samples were obtained and concentrations of plasma progesterone (P) were measured. Immunization against 3α-diol significantly increased the ovulation rate after the second and third immunizations and at week 10 (P<0.01, P<0.01 and P<0.05 respectively). It also induced anovulation in several ewes. Plasma concentrations of P were significantly increased by 3α-diol immunization (P<0.01). Pulse frequency of LH and concentrations of FSH were also increased during the luteal phase (P<0.01 and P<0.05 respectively). There was a significant correlation between the mean concentrations of FSH during the luteal phase and the subsequent ovulation rates (P<0.01). These results indicate that immunization against 3α-diol increases ovulation rate in ewes and its effect was, at least partially, exerted by increased plasma concentrations of FSH. | |||||||||
言語 | en | |||||||||
書誌情報 |
en : Journal of Reproduction and Development 巻 47, 号 1, p. 7-15, 発行日 2001 |
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出版者 | Japanese Society of Animal Reproduction | |||||||||
言語 | en | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 09168818 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA10936678 | |||||||||
DOI | ||||||||||
関連タイプ | isIdenticalTo | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | info:doi/10.1262/jrd.47.7 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | Japanese Society of Animal Reproduction | |||||||||
フォーマット | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
著者版フラグ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |