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The epidemiological survey for atovaquone resistant related gene of Babesia gibsoni in Japan
https://obihiro.repo.nii.ac.jp/records/1194
https://obihiro.repo.nii.ac.jp/records/11945a9bc2c8-9048-4162-bdf8-7e6eff24a460
名前 / ファイル | ライセンス | アクション |
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78_15-0480.pdf (513.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2017-08-16 | |||||||||
タイトル | ||||||||||
言語 | en | |||||||||
タイトル | The epidemiological survey for atovaquone resistant related gene of Babesia gibsoni in Japan | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | allele-specific real-time PCR | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Babesia gibsoni | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | drug resistance | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | M121I variant population | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
Iguchi, Aiko
× Iguchi, Aiko× Soma, Takehisa× Suzuki, Hiroshi× 玄, 学南
WEKO
295
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | In 73 gDNA samples from Babesia gibsoni-infected dogs, the M121I variant population was measured by using allele-specific real-time PCR. Although the mechanism of atovaquone against B. gibsoni has not been clearly identified, it is reported that the mitochondria cytochrome b gene of the atovaquone-resistant B. gibsoni had a single-nucleotide substitution at nt363 (G to T), which resulted in the substitution of methionine with isoleucine (M121I). In this study, 3/73 samples showed over 5% M121I variant population. Although the M121I variant population is a low percentage, it runs the risk of spreading drug-resistant parasites. It is important to prevent the spread of drug-resistance, so we need to gather information about this at regular intervals. | |||||||||
言語 | en | |||||||||
書誌情報 |
en : Journal of Veterinary Medical Science 巻 78, 号 3, p. 489-491, 発行日 2016-03 |
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出版者 | ||||||||||
言語 | en | |||||||||
出版者 | Japanese Society of Veterinary Science | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 09167250 | |||||||||
書誌レコードID | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA10796138 | |||||||||
DOI | ||||||||||
関連タイプ | isIdenticalTo | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | info:doi/10.1292/jvms.15-0480 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License <http://creativecommons.org/licenses/by-nc-nd/4.0/>. | |||||||||
フォーマット | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
著者版フラグ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
日本十進分類法 | ||||||||||
主題Scheme | NDC | |||||||||
主題 | 649 |