@article{oai:obihiro.repo.nii.ac.jp:00000923, author = {Murakami, Tomoaki and Kobayashi, Yoshiyasu and 古林, 与志安 and Chiba, Shiori and 千葉, 史織 and Kurauchi, Yuki and Sakamoto, Hideyuki and Sasaki, Motoki and 佐々木, 基樹 and Matsui, Takane}, issue = {9}, journal = {Journal of Veterinary Medical Science}, month = {}, note = {application/pdf, Humeral chondrosarcoma was found in an 18-year-old male Hokkaido brown bear (Ursus arctos yesoensis). Necropsy revealed a large firm mass under the left superficial pectoral muscle at the axillary region. The mass involved the left shoulder joint and peripheral muscles, and connected to the head of the humerus with osteolysis. Histopathologically, the mass was composed of irregularly shaped myxomatous to cartilaginous tumor lobules. The tumor cell showed moderate nuclear atypia with a relatively high mitotic index, especially in the edges of the myxomatous lobules. The tumor cells were positively immunostained with vimentin and S-100 protein. Based on these findings, the tumors were diagnosed as chondrosarcoma. Metastases were found in the left axillary lymph node, lungs, liver and kidney.}, pages = {1195--1197}, title = {Humeral chondrosarcoma in a Hokkaido brown bear (Ursus arctos yesoensis).}, volume = {74}, year = {2012} }