{"created":"2023-05-15T15:15:20.883181+00:00","id":922,"links":{},"metadata":{"_buckets":{"deposit":"761321a7-0b40-4815-a8c2-1fd8f89d4999"},"_deposit":{"created_by":12,"id":"922","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"922"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00000922","sets":["5"]},"author_link":["331","17","1919","291"],"control_number":"922","item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"509","bibliographicPageStart":"498","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"化学と生物"},{"bibliographic_title":"Kagaku to Seibutsu","bibliographic_titleLang":"en"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"人乳にはラクトース以外のミルクオリゴ糖が初乳で22～24 g/L，常乳で12～13 g/L含まれ，これまでに115種類もの構造が解析されている．一方でウシでは分娩直後の初乳で1 g/L以上のミルクオリゴ糖が含まれ，そのうちの70%は3'-シアリルラクトースなどの酸性オリゴ糖が占めるが，とくに酸性オリゴ糖の含有量は分娩後48時間以降の乳では急減し，常乳中にはごく少量しか含まれていない．ウシミルクオリゴ糖の構造研究は，含まれる量がごく少量であることが原因でヒトミルクオリゴ糖の構造研究に比べて著しく遅れていたが，近年親水性相互作用高速液体クロマトグラフィーやエキソグリコシダーゼ消化、質量分析の組み合わせによる構造解析方法の進歩によって微量での解析が可能となった．一方で，新たな各ウシミルクオリゴ糖の定量分析方法も開発された．本解説では，ウシを中心とする家畜ミルクオリゴ糖構造研究の歴史的な展開，新たな構造情報や定量分析方法・定量分析値，ならびにウシミルク糖タンパク質糖鎖の解析方法・構造情報を紹介するとともに，将来的な家畜ミルクオリゴ糖やミルク複合糖質の産業面での利用可能性について展望する．","subitem_description_type":"Abstract"}]},"item_2_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"J-Stageにて公開","subitem_description_type":"Other"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本農芸化学会"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1271/kagakutoseibutsu.50.498","subitem_relation_type_select":"DOI"}}]},"item_2_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://doi.org/10.1271/kagakutoseibutsu.50.498"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://doi.org/10.1271/kagakutoseibutsu.50.498","subitem_relation_type_select":"DOI"}}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本農芸化学会"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00037573","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0453073X","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{}],"affiliationNames":[{}]}],"creatorNames":[{"creatorName":"Urashima, Tadasu","creatorNameLang":"en"},{"creatorName":"浦島, 匡","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"朝隈, 貞樹","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{}],"affiliationNames":[{}]}],"creatorNames":[{"creatorName":"Fukuda, Kenji","creatorNameLang":"en"},{"creatorName":"福田, 健二","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Saito, Tadao","creatorNameLang":"en"},{"creatorName":"齋藤, 忠夫","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ウシをはじめとする家畜ミルクオリゴ糖研究の最近の進歩","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ウシをはじめとする家畜ミルクオリゴ糖研究の最近の進歩","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"12","path":["5"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-06-30"},"publish_date":"2015-06-30","publish_status":"0","recid":"922","relation_version_is_last":true,"title":["ウシをはじめとする家畜ミルクオリゴ糖研究の最近の進歩"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-03-11T00:48:33.808856+00:00"}