@article{oai:obihiro.repo.nii.ac.jp:00000060,
 author = {Miyahara, Kazuro and 宮原, 和郎 and Matsumoto, Toru and Tose, Shinichi and Sakurai, Haruhisa and Igarashi, Ikuo and 五十嵐, 郁男 and Saito, Atsushi and Hirose, Tsuneo and 広瀬, 恒夫 and Suzuki, Naoyoshi},
 issue = {1},
 journal = {Journal of Veterinary Medical Science},
 month = {},
 note = {application/pdf, Spleen cells from Toxoplasma lysate antigen (TLA)-sensitized BALB/c mice showed the strong cytotoxic activity against both natural killer (NK)-sensitive cells (YAC-1 and RL♂-1) and NK-insensitive cells (P-815), when incubated with TLA or recombinant human IL-2 (rhIL-2). The increment of TLA concentration in culture medium increased the cytotoxic activity. Treatment of effector cells; spleen cells from TLA-sensitized mice incubated with TLA, with anti-asialo GM1 or anti-Thy-1 plus complement inhibited the cytotoxic activity of effector cells, whereas treatment with anti-mouse Lyt-2.2 serum plus complement had no effect on the cytotoxic activity. Treatment of spleen cells from TLA-sensitized mice with anti-asialo GM1 and/or anti-Thy-1 plus complement inhibited cytotoxic activities of effector cells. These results suggested that spleen bells sensitized with TLA both in vivo and in vitro were asialo GM1 positive and Thy-1 positive; and the majority of cytotoxic cells induced by TLA were similar to lymphokine-activated killer (LAK)cells induced by IL-2.},
 pages = {87--93},
 title = {Characteristics of Cytotoxic Cells Induced by Toxoplasma Lysate Antigen in Mouse Spleen},
 volume = {54},
 year = {1992}
}