{"created":"2023-05-15T15:15:03.227185+00:00","id":549,"links":{},"metadata":{"_buckets":{"deposit":"649a57a5-25a2-41aa-8b43-b490dd87f79e"},"_deposit":{"created_by":12,"id":"549","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"549"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00000549","sets":["5"]},"author_link":[],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"An Experimental Study to Investigate the Suppressive Effect of Hatakeshimeji (Lyophyllum decastes Sing.) Extract on Carboplatin-induced Myelosuppression","subitem_alternative_title_language":"en"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"89","bibliographicPageStart":"87","bibliographicVolumeNumber":"17","bibliographic_titles":[{"bibliographic_title":"動物臨床医学","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of Animal Clinical Medicine","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ハタケシメジ抽出物の白血球数調節作用を調べる目的でハタケシメジ抽出物を経口投与し，カルボプラチン投与後の骨髄抑制作用の違いを5週間にわたる経時的な血液検査により検討した。その結果，総白血球数および好中球数においてハタケシメジ抽出物投与群がプラセボ投与群に対して有意に高値を示した。このことより，カルボプラチンによる骨髄抑制に対して，ハタケシメジ抽出物が白血球数減少抑制作用を有することが確認された。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"In order to elucidate the suppressive  effect of Hatakeshimeji (Lyophyllum decastes Sing.) extract on leukocytopenia，the degree of carboplatin-induced myelosuppression was compared between two groups of dogs; each group was daily given Hatakeshimeji extract or only its placebo for 5 weeks，and on day 7， carboplatin，an anticancer agent，was given intravenously to all dogs. Hematological analyses revealed that the nunbers of leukocytes and neutrophils were both significantly higher in the group given Hatakeshimeji extract than in the placebo group. This indicated that Hatakeshimeji extract can suppress carboplatin-induced myelosuppression.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"動物臨床医学研究所","subitem_publisher_language":"ja"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.11252/dobutsurinshoigaku.17.87","subitem_relation_type_select":"DOI"}}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"動物臨床医学研究所","subitem_rights_language":"ja"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10478688","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13446991","subitem_source_identifier_type":"PISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"清水, 純一郎","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"持田, 恭平","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"岸本, 海織","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"李, 奇子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"池水, 智博","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"室谷, 直義","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"小嶋, 靖","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"山田, 一孝","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-30"}],"displaytype":"detail","filename":"hatake.pdf","filesize":[{"value":"117.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"hatake.pdf","url":"https://obihiro.repo.nii.ac.jp/record/549/files/hatake.pdf"},"version_id":"065ff96a-1bc4-4e08-9f2e-04f8a6189a62"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"カルボプラチン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"犬","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ハタケシメジ抽出物","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"carboplatin","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"dog","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Hatakeshimeji extract","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ハタケシメジ抽出物によるカルボプラチン投与後の白血球数減少抑制作用についての基礎的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ハタケシメジ抽出物によるカルボプラチン投与後の白血球数減少抑制作用についての基礎的研究","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"12","path":["5"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-05-25"},"publish_date":"2011-05-25","publish_status":"0","recid":"549","relation_version_is_last":true,"title":["ハタケシメジ抽出物によるカルボプラチン投与後の白血球数減少抑制作用についての基礎的研究"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-02-28T03:06:14.879879+00:00"}