{"created":"2023-05-15T15:18:27.001286+00:00","id":4822,"links":{},"metadata":{"_buckets":{"deposit":"a1701e42-dccf-4fe0-bd49-e659014b97a8"},"_deposit":{"created_by":12,"id":"4822","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"4822"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00004822","sets":["5"]},"author_link":["6736","6737","6738","6739","6740","6741","6742","6743","6746","6745"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"219","bibliographicPageStart":"210","bibliographicVolumeNumber":"42","bibliographic_titles":[{"bibliographic_title":"Carcinogenesis","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Fucoxanthin (Fx), a marine carotenoid found in edible brown algae, is well known for having anticancer properties. The gut microbiota has been demonstrated as a hallmark for colorectal cancer progression in both humans and rodents. However, it remains unclear whether the gut microbiota is associated with the anticancer effect of Fx. We investigated the chemopreventive potency of Fx and its effect on gut microbiota in a mouse model of inflammation-associated colorectal cancer (by azoxymethane/dextran sulfate sodium treatment). Fx administration (30 mg/kg bw) during a 14 week period significantly inhibited the multiplicity of colorectal adenocarcinoma in mice. The number of apoptosis-like cleaved caspase-3high cells increased significantly in both colonic adenocarcinoma and mucosal crypts. Fx administration significantly suppressed Bacteroidlales (f_uc; g_uc) (0.3-fold) and Rikenellaceae (g_uc) (0.6-fold) and increased Lachnospiraceae (g_uc) (2.2-fold), compared with those of control mice. Oral administration of a fecal suspension obtained from Fx-treated mice, aimed to enhance Lachnospiraceae, suppress the number of colorectal adenocarcinomas in azoxymethane/dextran sulfate sodium-treated mice with a successful increase in Lachnospiraceae in the gut. Our findings suggested that an alteration in gut microbiota by dietary Fx might be an essential factor in the cancer chemopreventive effect of Fx in azoxymethane/dextran sulfate sodium-treated mice.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Oxford University Press"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1093/carcin/bgaa100\tDOI\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tapplication/pdf\t\tOther\thttp://purl.org/coar/version/c_ab4af688f83e57aa\tAM\t491\t\tNDC\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tmiyashita_42(2)210-219_202102.pdf\t335.1 kB\tapplication/pdf\t\t\tlicense_note\tFull text\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/miyashita_42(2)210-219_202102.pdf\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tFigure 1_Terasaki M.jpg\t1.9 MB\timage/jpeg\t\t\tlicense_note\tFigure 1\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Figure 1_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tFigure 2_Terasaki M.jpg\t1.3 MB\timage/jpeg\t\t\tlicense_note\tFigure 2\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Figure 2_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tFigure 3_Terasaki M.jpg\t369.9 kB\timage/jpeg\t\t\tlicense_note\tFigure 3\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Figure 3_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tFigure 4_Terasaki M.jpg\t903.2 kB\timage/jpeg\t\t\tlicense_note\tFigure 4\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Figure 4_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tFigure 5_Terasaki M.jpg\t1.3 MB\timage/jpeg\t\t\tlicense_note\tFigure 5\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Figure 5_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Table 1_Terasaki M.pdf\t100.6 kB\tapplication/pdf\t\t\tlicense_note\tSupplementary Table 1\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Table 1_Terasaki M.pdf\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Table 2_Terasaki M.pdf\t101.4 kB\tapplication/pdf\t\t\tlicense_note\tSupplementary Table 2\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Table 2_Terasaki M.pdf\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Figure 1_Terasaki M.jpg\t407.0 kB\timage/jpeg\t\t\tlicense_note\tSupplementary Figure 1\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Figure 1_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Figure 2_Terasaki M.jpg\t1.3 MB\timage/jpeg\t\t\tlicense_note\tSupplementary Figure 2\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Figure 2_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Figure 3_Terasaki M.jpg\t1.5 MB\timage/jpeg\t\t\tlicense_note\tSupplementary Figure 3\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Figure 3_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Figure 4_Terasaki M.jpg\t1.4 MB\timage/jpeg\t\t\tlicense_note\tSupplementary Figure 4\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Figure 4_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Figure 5_Terasaki M.jpg\t1.2 MB\timage/jpeg\t\t\tlicense_note\tSupplementary Figure 5\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Figure 5_Terasaki M.jpg\t\t\topen_date\tAvailable\t2022-11-01\tdetail\t\t\tSupplementary Figure 6_Terasaki M.jpg\t431.1 kB\timage/jpeg\t\t\tlicense_note\tSupplementary Figure 6\t\thttps://obihiro.repo.nii.ac.jp/record/4822/files/Supplementary Figure 6_Terasaki M.jpg\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tScopus202209-07; 2022/9/28宮下先生に依頼(著者版);2022/10/11 OK，ファイル提供; 2022/11/1登録; エンバーゴ 2022/2/1;\n\n\t\t宮下 和夫 miyashitak@obihiro.ac.jp\n4825\thttps://obihiro.repo.nii.ac.jp/records/4825\t5\t学術雑誌論文\tpublic\tkondoh-d@obihiro.ac.jp\t\t\t\t\t\t\tKeep\t2022-11-10\tThe nasal cavity in sea turtles: adaptation to olfaction and seawater flow\ten\teng\tMarine lifestyle · Olfaction · Respiration · Sensory epithelium · Vomeronasal organ\ten\tOther\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tjournal article\thttp://purl.org/coar/resource_type/c_6501\t\t\t\t\t\t\t\tISNI\thttp://www.isni.org/isni/\t\tja\t\t\tkondoh-d@obihiro.ac.jp\tKondoh, Daisuke\ten\t近藤, 大輔\tja\tKondoh\ten\t近藤\tja\tDaisuke\ten\t大輔\tja\t329\tWEKO\t\t9000002683176\tCiNii ID\thttp://ci.nii.ac.jp/nrid/9000002683176\t90708364\te-Rad\thttps://kaken.nii.ac.jp/ja/search/?qm=90708364\t0000-0002-3015-5156\tORCID\thttps://orcid.org/0000-0002-3015-5156\t\t\t\t\t\t\t\t\t\t\t\tKitayama, Chiyo\ten\t\t\t\t\t\t\t\t\t\t\t2266\tWEKO\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tykawai@obihiro.ac.jp\tKawai, Yusuke\ten\t\t\t\t\t\t\t\t\t\t\t370\tWEKO\t\t9000283730286\tCiNii ID\thttp://ci.nii.ac.jp/nrid/9000283730286\t10709546\te-Rad\thttps://kaken.nii.ac.jp/ja/search/?qm=10709546\tfiddler_K\tresearchmap\thttps://researchmap.jp/fiddler_K\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tThe nasal cavity of tetrapods has become phylogenetically adapted to the environment in terms of function, respiration, and olfaction. In addition, the nasal cavity of sea turtles plays an important role in seawater flow and water olfaction, unlike that of terrestrial species. Here, we describe the functional, morphological, and histological characteristics of the nasal cavity, and the odorant receptors encoded in the genome of sea turtles. The nasal cavity of sea turtles is well-suited to its complicated functions, and it significantly differs from those of other animals, including terrestrial and semi-aquatic turtles.\ten\tAbstract\t\t\t\t2021-01-06\tIssued\t1\t\t352\t347\t383 \t\t\tCell and Tissue Research\ten\tSpringer\t\t0302766X\tISSN\t\t\t\t\t\tAA00600105\tNCID\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tisVersionOf\tinfo:doi/10.1007/s00441-020-03353-z","subitem_relation_type_select":"DOI"}}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12072343","subitem_source_identifier_type":"NCID"}]},"item_2_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"487","subitem_subject_scheme":"NDC"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Terasaki, Masaru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uehara, Osamu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ogasa, Shinya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sano, Taishi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kubota, Atsuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kojima, Hiroyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanaka, Takuji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Hayato","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyashita, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Mutoh, Michihiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-11-10"}],"displaytype":"detail","filename":"kondo_383(1)347-352_202101.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","url":{"label":"Full text","url":"https://obihiro.repo.nii.ac.jp/record/4825/files/kondo_383(1)347-352_202101.pdf"},"version_id":""}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"inflammation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"colorectal","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cancer feces","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mice","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"chemopreventive agents","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microbiome","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["5"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-11-01"},"publish_date":"2022-11-01","publish_status":"0","recid":"4822","relation_version_is_last":true,"title":["Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-02-28T03:01:32.145894+00:00"}