{"created":"2023-05-15T15:18:22.881536+00:00","id":4735,"links":{},"metadata":{"_buckets":{"deposit":"29a0259e-955e-4762-a90f-0fb59929557e"},"_deposit":{"created_by":12,"id":"4735","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"4735"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00004735","sets":["5"]},"author_link":["6636","6640","6639","6642","6644","6638","6637","6641"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"667","bibliographicPageStart":"655","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Beneficial Microbes","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Lactobacillus plantarum Shinshu N-07 (N07) and Lactobacillus curvatus #4G2 (#4G2)\nwere isolated from fermented Brassica rapa L. and selected as promising probiotics\nwith anti-adiposity activities based on in vitro assays. The anti-adiposity effects of these\ntwo strains were investigated using a diet-induced obesity animal model. Epididymal\nadipose tissue weight and adipocyte area were significantly lower and serum\ntriglycerides and glucose tended to be lower in mice fed the high-fat diet supplemented\nwith N07 compared with those fed the unsupplemented high-fat diet. Strain N07\nsuppressed hepatic steatosis, with accompanying downregulation of lipogenic genes in\nthe liver. Expression of inflammatory cytokines and macrophage infiltration markers\ntended to be suppressed by N07 supplementation. Upregulation of uncoupling protein-1\nin epididymal adipose tissue by N07 suggested that the transformation of white adipose\ntissue to brown might have been induced. Intestinal microbiota analysis revealed that a\ndecrease in abundance of family S24-7 (phylum Bacteroidetes) following ingestion of\nthe high-fat diet was partly recovered by supplementation with N07. Changes in those\nparameters were not observed in mice fed the high-fat diet supplemented with strain\n#4G2, suggesting strain specificities. Thus, N07 is a potential probiotic strain that could\nbe used to develop functional foods that attenuate visceral fat accumulation after an\nappropriate human intervention trial.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wageningen Academic Publishers","subitem_publisher_language":"en"}]},"item_2_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"33045842","subitem_relation_type_select":"PMID"}}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.3920/BM2020.0009","subitem_relation_type_select":"DOI"}}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"The original publication is available at https://www.wageningenacademic.com/doi/10.3920/BM2020.0009.","subitem_rights_language":"en"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12759642","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"18762883","subitem_source_identifier_type":"PISSN"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yin, J","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6636","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Bayanjargal, S","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6637","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fang, B","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6638","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inaba, C","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6639","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mutoh, M","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6640","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawahara, T","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6641","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tanaka, S","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6642","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Watanabe, Jun","creatorNameLang":"en"},{"creatorName":"渡辺, 純","creatorNameLang":"ja"}],"familyNames":[{"familyName":"Watanabe","familyNameLang":"en"},{"familyName":"渡辺","familyNameLang":"ja"}],"givenNames":[{"givenName":"Jun","givenNameLang":"en"},{"givenName":"純","givenNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"6644","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-05-24"}],"displaytype":"detail","filename":"BeneficialMicrobes_author_final_MS.pdf","filesize":[{"value":"5.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"fulltext","url":"https://obihiro.repo.nii.ac.jp/record/4735/files/BeneficialMicrobes_author_final_MS.pdf"},"version_id":"77bd114b-32cf-470c-9048-f86c398d8fe7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"fermented Brassica rapa L.","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"anti-adiposity effect","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Lactobacillus plantarum","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"high-fat diet","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intestinal microbiota","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Lactobacillus plantarum Shinshu N-07 isolated from fermented Brassica rapa L. attenuates visceral fat accumulation induced by high-fat diet in mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Lactobacillus plantarum Shinshu N-07 isolated from fermented Brassica rapa L. attenuates visceral fat accumulation induced by high-fat diet in mice","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["5"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-05-24"},"publish_date":"2021-05-24","publish_status":"0","recid":"4735","relation_version_is_last":true,"title":["Lactobacillus plantarum Shinshu N-07 isolated from fermented Brassica rapa L. attenuates visceral fat accumulation induced by high-fat diet in mice"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-12-04T02:28:16.630108+00:00"}