{"created":"2023-05-15T15:18:14.320356+00:00","id":4540,"links":{},"metadata":{"_buckets":{"deposit":"cc59ab2c-d6a3-47f1-b59e-f49bcc83ffca"},"_deposit":{"created_by":12,"id":"4540","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"4540"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00004540","sets":["5"]},"author_link":["168","291"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"家畜のミルクオリゴ糖","subitem_alternative_title_language":"ja"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"88","bibliographicPageEnd":"142","bibliographicPageStart":"135","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"Trends in Glycoscience and Glycotechnology","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Milk is the only food for the newborn young, and it contains many nutritious as well as biofunctional components which are available for the homeostasis and health of the immature newborn infants. People have been collecting the milk from several domestic animals such as cows, sheep, goats and horses in order to utilize them as raw foods or dairy products. Milk oligosaccharides, which are one of milk's components, have recently been recognized as significant anti-infectional compounds against pathogenic viruses and bacteria as well as being an energy source for the newborn young. They may also be materials which are required for the postnatal biosynthesis of glycoconjugates, particularly of the nervous system. It is concluded that the domestic animals' milk or colostrum are available to separate several biofunctional materials. Milk/colostrum of domestic animals, especially colostrum, contains large amounts of sialyl oligosaccharides as well as many kinds of neutral oligosaccharides. The colostrum should therefore be suitable as raw material for the large-scale preparation of milk oligosaccharides. Improved separation techniques will stimulate their utilisation in the pharmacological and food industries. Many types of oligosaccharides will also be used within an oligosaccharide library to help in determining the epitopes of several types of lectins or antibodies and clarifying the features of glycosyltransferases and glycosidases.","subitem_description_type":"Abstract"},{"subitem_description":"乳は新生児にとって唯一の食糧であり､そのため多くの栄養素とともに未成熟な新生児の健康や恒常性の維持に必要な生物学的機能性成分が含まれている｡ヒトはウシ､ヒツジ､ヤギ､ウマと言った様々な家畜から乳を採取し､市乳または乳加工品として利用している｡乳成分の1つであるミルクオリゴ糖には､近年､新生児に対する栄養源としてばかりでなく感染性のウイルスや細菌に対する抗感染物質としての意義が認められてきている｡また､ミルクオリゴ糖は乳児の体内複合糖質､とくに神経系の複合糖質の生合成に必要な物質でもある｡家畜の乳は各種の生理活性物質の分離源として有用である｡これらの家畜の乳､特に初乳中には数多くの中性オリゴ糖のほか､大量のシアリルオリゴ糖が含まれている｡したがって､家畜の初乳はミルクオリゴ糖を大量調製するための原料として適している｡分離技術の向上により､製薬や食品産業へのこれらミルクオリゴ糖の利用が可能となるであろう｡多種多様なオリゴ糖からなる｢オリゴ糖ライブラリー｣の構築は､様々なタイプのレクチンや抗体のエピトープ解析や､糖転移酵素や糖加水分解酵素の研究にも有用であろう｡","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Forum: Carbohydrates Coming of Age(FCCA)"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.4052/tigg.16.135","subitem_relation_type_select":"DOI"}}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10995236","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09157352","subitem_source_identifier_type":"ISSN"}]},"item_2_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"648","subitem_subject_scheme":"NDC"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakamura, Tadashi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{}],"affiliationNames":[{}]}],"creatorNames":[{"creatorName":"Urashima, Tadasu","creatorNameLang":"en"},{"creatorName":"浦島, 匡","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-12-02"}],"displaytype":"detail","filename":"Vol.16(88),135-142.pdf","filesize":[{"value":"2.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"fulltext","url":"https://obihiro.repo.nii.ac.jp/record/4540/files/Vol.16(88),135-142.pdf"},"version_id":"7b2adccd-c8e4-42b6-a8e9-6bb78bf4e35b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cow","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Domestic animal","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Goat","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Horse","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Lactation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Milk oligosaccharides","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Sheep","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The milk oligosaccharides of domestic farm animals","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The milk oligosaccharides of domestic farm animals","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["5"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-12-02"},"publish_date":"2019-12-02","publish_status":"0","recid":"4540","relation_version_is_last":true,"title":["The milk oligosaccharides of domestic farm animals"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-02-28T03:07:06.722327+00:00"}