@article{oai:obihiro.repo.nii.ac.jp:00000379,
 author = {Hashimoto, Naoto and 橋本, 直人 and Ito, Yusaku and Han, Kyu-ho and 韓, 圭鎬 and Shimada, Kenichiro and 島田, 謙一郎 and Sekikawa, Mitsuo and Topping, David L. and Bird, Anthony R. and Noda, Takahiro and Chiji, Hideyuki and Fukushima, Michihiro and 福島, 道広},
 issue = {6},
 journal = {Journal of Nutritional Science and Vitaminology},
 month = {},
 note = {application/pdf, In our previous study, we demonstrated that retrograded starch, a kind of resistant starch, of beans reduced serum lipid levels in rats. In this study, we examined whether retrograded starch in potato pulps could reduce serum lipid concentrations. Rats were given diets containing 15 g of retrograded starch in potato pulps from the Benimaru potato (BM) or Hokkaikogane potato (HK) in a 100 g diet for 4 wk. At the 4th week, the total cholesterol level in the serum in the BM group and serum triglyceride (TG) level in the HK group were significantly lower than those in the control group. In the BM group, the contents of fecal bile acids were significantly higher than those in the control group. On the other hand, in the HK group, the hepatic mRNA level of fatty acid synthase (FAS) was significantly lower than that in the control group. The FAS mRNA level correlated with the mRNA level of sterol regulatory element-binding protein-1c (SREBP-1c), a regulator of expression of FAS, positively. These results suggested that BM pulp promoted the excretion of bile acids, which resulted in a low concentration of serum cholesterol. On the other hand, HK pulp inhibited the synthesis of fatty acids at the mRNA levels of FAS and SREBP-1c, which might lead to a reduction of the serum TG level., 日本ビタミン学会、日本栄養・食糧学会共同編集},
 pages = {445--450},
 title = {Potato Pulps Lowered the Serum Cholesterol and Triglyceride Levels in Rats},
 volume = {52},
 year = {2006}
}