{"created":"2023-05-15T15:17:01.205691+00:00","id":3025,"links":{},"metadata":{"_buckets":{"deposit":"5e7e751e-c894-4632-8669-8b1167cc1659"},"_deposit":{"created_by":12,"id":"3025","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"3025"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00003025","sets":["242:243"]},"author_link":["176"],"item_6_alternative_title_1":{"attribute_name":"その他（別言語等）の研究課題名","attribute_value_mlt":[{"subitem_alternative_title":"Study of lipid metabolism network between Toxoplasma and hosts","subitem_alternative_title_language":"en"}]},"item_6_description_10":{"attribute_name":"研究代表者番号","attribute_value_mlt":[{"subitem_description":"90431395","subitem_description_type":"Other"}]},"item_6_description_11":{"attribute_name":"研究機関","attribute_value_mlt":[{"subitem_description":"帯広畜産大学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_6_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究計画は、人獣共通感染症を引き起こすトキソプラズマにおける、原虫—宿主間での脂質代謝ネットワークの解明を目指したものである。本研究で、トキソプラズマは利己的に宿主脂質代謝を制御し、増殖ステージに応じてコレステロール資源を使い分けていることが明らかとなった。さらに、非感染細胞での過剰な脂質の蓄積は宿主細胞死を誘導することを見出した。本結果は、トキソプラズマの生存戦略の一つとして宿主脂質代謝の制御が関与していることを示している。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_6_description_14":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"2007年度～2008年度科学研究費補助金特定領域研究研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_6_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_6_description_9":{"attribute_name":"研究課題番号","attribute_value_mlt":[{"subitem_description":"19041008","subitem_description_type":"Other"}]},"item_6_text_12":{"attribute_name":"助成元","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"科学研究費助成事業"}]},"item_6_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-30"}],"displaytype":"detail","filename":"19041008seika.pdf","filesize":[{"value":"228.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"19041008seika.pdf","url":"https://obihiro.repo.nii.ac.jp/record/3025/files/19041008seika.pdf"},"version_id":"a3617c53-4964-4e56-a3f9-0021d375948a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"トキソプラズマ","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"脂質代謝","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"コレステロール","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"アポトーシス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"プロテオーム","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"抗原虫薬","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_researcher":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Nishikawa, Yoshifumi","creatorNameLang":"en"},{"creatorName":"西川, 義文","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{},{},{}]}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"トキソプラズマ原虫と宿主間での脂質代謝ネットワークの解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"トキソプラズマ原虫と宿主間での脂質代謝ネットワークの解明","subitem_title_language":"ja"}]},"item_type_id":"6","owner":"12","path":["243"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-12-22"},"publish_date":"2010-12-22","publish_status":"0","recid":"3025","relation_version_is_last":true,"title":["トキソプラズマ原虫と宿主間での脂質代謝ネットワークの解明"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-02-20T07:45:26.178859+00:00"}