{"created":"2023-05-15T15:15:58.972453+00:00","id":1717,"links":{},"metadata":{"_buckets":{"deposit":"0b18ecde-c204-4cab-a303-c045e78b2d63"},"_deposit":{"created_by":12,"id":"1717","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"1717"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00001717","sets":["12:71"]},"author_link":["3963","3964"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"67","bibliographicPageStart":"53","bibliographicVolumeNumber":"2","bibliographic_titles":[{"bibliographic_title":"The journal of protozoology research","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Mononuclear cells, CD2+ T cells and T subsets (CD4+, CD8+) from HLA-typed malaria-naive donors were stimulated with isolated surface antigens (Ags) from Plasmodium falciparum merozoites (MSP183, MSP136, MSP2). Cell responses in lymphocyte proliferation assays were MHC-class II and mainly DR restricted. Donors could be grouped into high, non or low responders according to the proliferative response. The high responders possessed the combination DR7/DRw53 as a common HLA-restriction element. Non and low responders did not have this Ag combination, but some were characterized by DQwl. Individual donors did not show any Ag dependent response. CD45RA+ (naive, non-stimulated) enriched T cells from high-responders were strongly stimulated by the merozoite Ags, whereas stimulation of CD45RO+ (memory) enriched T cells was much lower.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Research Center for Protozoan Molecular Immunology","subitem_publisher_language":"en"}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Research Center for Protozoan Molecular Immunology","subitem_rights_language":"en"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10824856","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09174427","subitem_source_identifier_type":"PISSN"}]},"item_2_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"649","subitem_subject_scheme":"NDC"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Goerlich, Roland","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Heidrich, Hans-G.","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-30"}],"displaytype":"detail","filename":"Prot.Vol.2-2-2.pdf","filesize":[{"value":"546.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Prot.Vol.2-2-2.pdf","url":"https://obihiro.repo.nii.ac.jp/record/1717/files/Prot.Vol.2-2-2.pdf"},"version_id":"20781dec-0b91-43ac-ba1f-03ad30d32750"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Plasmodium falciparum","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"proliferative response","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"T subsets","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"merozoite antigens","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Proliferative Responses of T Subsets from Malaria-naive Human Donors [CD4+, CD8+, and Naive T Cell (CD45RA+)-enriched and Memory T Cell (CD45RO+)-enriched Subpopulations], to Plasmodium falciparum Polypeptide Antigens Isolated from the Merozoite Stage","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Proliferative Responses of T Subsets from Malaria-naive Human Donors [CD4+, CD8+, and Naive T Cell (CD45RA+)-enriched and Memory T Cell (CD45RO+)-enriched Subpopulations], to Plasmodium falciparum Polypeptide Antigens Isolated from the Merozoite Stage","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["71"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2006-12-21"},"publish_date":"2006-12-21","publish_status":"0","recid":"1717","relation_version_is_last":true,"title":["Proliferative Responses of T Subsets from Malaria-naive Human Donors [CD4+, CD8+, and Naive T Cell (CD45RA+)-enriched and Memory T Cell (CD45RO+)-enriched Subpopulations], to Plasmodium falciparum Polypeptide Antigens Isolated from the Merozoite Stage"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-10-26T07:40:54.455702+00:00"}