@article{oai:obihiro.repo.nii.ac.jp:00001717,
 author = {Goerlich, Roland and Heidrich, Hans-G.},
 issue = {2},
 journal = {The journal of protozoology research},
 month = {Apr},
 note = {application/pdf, Mononuclear cells, CD2+ T cells and T subsets (CD4+, CD8+) from HLA-typed malaria-naive donors were stimulated with isolated surface antigens (Ags) from Plasmodium falciparum merozoites (MSP183, MSP136, MSP2). Cell responses in lymphocyte proliferation assays were MHC-class II and mainly DR restricted. Donors could be grouped into high, non or low responders according to the proliferative response. The high responders possessed the combination DR7/DRw53 as a common HLA-restriction element. Non and low responders did not have this Ag combination, but some were characterized by DQwl. Individual donors did not show any Ag dependent response. CD45RA+ (naive, non-stimulated) enriched T cells from high-responders were strongly stimulated by the merozoite Ags, whereas stimulation of CD45RO+ (memory) enriched T cells was much lower.},
 pages = {53--67},
 title = {Proliferative Responses of T Subsets from Malaria-naive Human Donors [CD4+, CD8+, and Naive T Cell (CD45RA+)-enriched and Memory T Cell (CD45RO+)-enriched Subpopulations], to Plasmodium falciparum Polypeptide Antigens Isolated from the Merozoite Stage},
 volume = {2},
 year = {1992}
}