{"created":"2023-05-15T15:15:49.899743+00:00","id":1516,"links":{},"metadata":{"_buckets":{"deposit":"28f4bd34-0442-43b2-a633-b25e1cb06e29"},"_deposit":{"created_by":12,"id":"1516","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"1516"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00001516","sets":["12:31"]},"author_link":["58","3289","312","351"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"60","bibliographicPageStart":"56","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"The journal of protozoology research","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Recently，we reported the in vitro growth inhibitory effects of the imidazole derivatives，clotrimazole(CLT) and ketoconazole (KC)，and the herbicide，clodinafop-propargyl(CP)，against bovine and equine Babesia parasites. Additionally，in the bovine species，several combined applications of the CLT，KC，and CP were reported to significantly increase the inhibitory effects. In this study，similar combination tests were carried out in order to confirm possible synergistic effects in the equine species，Babesia caballi and Babesia equi. Combinations of CLT/KC， CLT/CP，and CLT/KC/CP exerted a significantly enhanced growth inhibitory efficacy in B. caballi，in contrast to B. equi，where no synergistic effects were observed in any of the combinations. Our results suggest that the combined usage of these drugs may have a high enough potential to be considered applicable in practice.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"National Research Center for Protozoan Diseases"}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"National Research Center for Protozoan Diseases","subitem_rights_language":"en"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10824856","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09174427","subitem_source_identifier_type":"PISSN"}]},"item_2_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"649","subitem_subject_scheme":"NDC"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Bork, Sabine","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{}],"affiliationNames":[{}]}],"creatorNames":[{"creatorName":"Yokoyama, Naoaki","creatorNameLang":"en"},{"creatorName":"横山, 直明","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Okamura, Masashi","creatorNameLang":"en"},{"creatorName":"岡村, 雅史","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Igarashi, Ikuo","creatorNameLang":"en"},{"creatorName":"五十嵐, 郁男","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-30"}],"displaytype":"detail","filename":"1222.pdf","filesize":[{"value":"245.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"1222.pdf","url":"https://obihiro.repo.nii.ac.jp/record/1516/files/1222.pdf"},"version_id":"b757fa44-dbe7-4ca5-bfaa-9a6933c7e154"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"in vitro","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Babesia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"clotrimazole","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ketoconazole","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"clodinafop-propargyl","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"IN VITRO GROWTH INHIBITORY EFFECTS OF COMBINED APPLICATIONS OF CLOTRIMAZOLE, KETOCONAZOLE, AND CLODINAFOP-PROPARGYL ON EQUINE BABESIA PARASITES","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"IN VITRO GROWTH INHIBITORY EFFECTS OF COMBINED APPLICATIONS OF CLOTRIMAZOLE, KETOCONAZOLE, AND CLODINAFOP-PROPARGYL ON EQUINE BABESIA PARASITES","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["31"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-01-25"},"publish_date":"2007-01-25","publish_status":"0","recid":"1516","relation_version_is_last":true,"title":["IN VITRO GROWTH INHIBITORY EFFECTS OF COMBINED APPLICATIONS OF CLOTRIMAZOLE, KETOCONAZOLE, AND CLODINAFOP-PROPARGYL ON EQUINE BABESIA PARASITES"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2024-01-23T07:55:52.385127+00:00"}