{"created":"2023-05-15T15:15:48.493852+00:00","id":1486,"links":{},"metadata":{"_buckets":{"deposit":"c1c2f65e-ab2f-4a15-9a59-173d668de82c"},"_deposit":{"created_by":12,"id":"1486","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"1486"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00001486","sets":["12:24"]},"author_link":["3175","3176","3177","3178","3179","3180","3181"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"24","bibliographicPageStart":"16","bibliographicVolumeNumber":"17","bibliographic_titles":[{"bibliographic_title":"The journal of protozoology research","bibliographic_titleLang":"en"}]}]},"item_2_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Meliae cortex (Melia azedarach Linne. var. japonica Makino, M. toosendan Siebold & Zucc) is one of the herbs used in oriental medicine for the treatment of various types of vaginitis. The present study was performed to examine the effects of Meliae cortex extracts on the growth and fine structure of Trichomonas vaginalis (T. vaginalis).\nMeliae cortex dose-dependently reduced the viability of T. vaginalis. In the electron microscopy study, we also observed the ultrastructural changes of T. vaginalis following the treatment with Meliae cortex. One to two hours after the addition of the extract of Meliae cortex, the movement of flagella and axostyle decreased, but the cell death did not occur. The fine structure of the cytoplasm was changed 30 min to 2 hour after the treatment of the extract of Meliae cortex. The number of polyribosome decreased, whereas the number of single ribosomes in the cytoplasm increased. \nThese results indicate that Meliae cortex has the antiprotozoal effects on T. vaginalis cells through the inhibition of cell multiplication as well as the impairment of protein synthesis.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"National Research Center for Protozoan Diseases","subitem_publisher_language":"en"}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"National Research Center for Protozoan Diseases","subitem_rights_language":"en"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10824856","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09174427","subitem_source_identifier_type":"PISSN"}]},"item_2_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"649","subitem_subject_scheme":"NDC"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Lee, Yun Sik","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chung, In Bai","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Choi, Won Hyung","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Cho, Yoo Jung","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chu, Jong Phil","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Min, Byung-Il","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shin, Eun-Hee","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-30"}],"displaytype":"detail","filename":"v17-1-3.pdf","filesize":[{"value":"169.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"v17-1-3.pdf","url":"https://obihiro.repo.nii.ac.jp/record/1486/files/v17-1-3.pdf"},"version_id":"29881368-a8b1-4f1e-b97e-24cdb8857ceb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Trichomonas vaginalis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Meliae cortex","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Meliae azedarach","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"inhibition of cell multiplication","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"protozoa","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ultra structure","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Inhibitory effects of Melia azedarach L. extracts on the growth of Trichomonas vaginalis : Ultrastructural changes of Trichomonas vaginalis treated by Melia azedarach L","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Inhibitory effects of Melia azedarach L. extracts on the growth of Trichomonas vaginalis : Ultrastructural changes of Trichomonas vaginalis treated by Melia azedarach L","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["24"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-07-26"},"publish_date":"2007-07-26","publish_status":"0","recid":"1486","relation_version_is_last":true,"title":["Inhibitory effects of Melia azedarach L. extracts on the growth of Trichomonas vaginalis : Ultrastructural changes of Trichomonas vaginalis treated by Melia azedarach L"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-08-22T07:21:12.907870+00:00"}