{"created":"2023-05-15T15:15:31.007292+00:00","id":1125,"links":{},"metadata":{"_buckets":{"deposit":"a8e490b8-4de8-487a-8b8c-6a9fb2647e70"},"_deposit":{"created_by":12,"id":"1125","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"1125"},"status":"published"},"_oai":{"id":"oai:obihiro.repo.nii.ac.jp:00001125","sets":["5"]},"author_link":["61","54","102"],"item_2_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Retrospective study of eleven Holstein dairy cows in which bovine leukosis was suspected but ruled 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BLV）抗体陽性を呈した4頭のうち，リンパ球増多症を呈したものが2頭であった．またこれら2頭のうち1頭はリンパ節細胞診でも大型リンパ球優勢であった．しかし，血清チミジンキナーゼ（Tymidine kinase: TK），総乳酸脱水素酵素（Lactate dehydrogenase: LDH），LDHアイソザイム2および3の活性値は4頭とも基準値以内であり，牛白血病発症は否定的であった．BLV抗体陰性牛7頭のうち，リンパ節細胞診を実施した2頭は小型リンパ球優勢であり，また，リンパ球増多症を呈した症例はいなかった．1症例では血清TK活性値が基準値をわずかに超えており，また，他の2頭は総LDH，LDHアイソザイム2および3の活性値がいずれも基準値を超えていたが，他の検査項目は牛白血病について否定的であった．腫大リンパ節の細胞診，リンパ球数算定，血清TK，総LDH，LDHアイソザイム2および3の活性値測定といった牛白血病診断のための検査を複数実施することで，牛白血病を否定するための診断精度を高めることが可能と考えられた．","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本家畜臨床学会, 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