@article{oai:obihiro.repo.nii.ac.jp:00001092, author = {Horiuchi, Noriyuki and 堀内, 雅之 and Komagata, Makoto and Shitamura, Keiichi and Chiba, Shiori and 千葉, 史織 and Matsumoto, Kohtaro and 松本, 高太郎 and Inokuma, Hisashi and 猪熊, 壽 and Matsui, Takane and Kobayashi, Yoshiyasu and 古林, 与志安}, issue = {6}, journal = {Journal of Veterinary Medical Science}, month = {}, note = {application/pdf, An 11-year-old Holstein-Friesian cow exhibited anorexia and jaundice. A large mass was found in the liver during necropsy. Macroscopically, the mass was composed of dark red multilobular tissue and a centrally located abscess, which was connected to the hepatic duct. Histologically, the mass consisted of proliferation of small neoplastic cells and was demarcated from the hepatic parenchyma by a thick region of granulation tissue. The neoplastic cells were predominantly arranged in solid sheets, but they also formed blood-filled cancellous structures, and proliferating foci were seen around blood vessels. Periodic acid-Schiff reaction demonstrated that a fine basement membrane-like structure surrounded the neoplastic cells. Immunohistochemically, the neoplastic cells were positive for vimentin and alpha smooth muscle actin and negative for cytokeratin, factor VIII-related antigen, chromogranin and desmin. Based on its histopathological features, the hepatic neoplasm was diagnosed as a primary glomus tumor. This is the first report about a primary glomus tumor of the liver in a cow.}, pages = {729--732}, title = {Glomus tumor of the liver in a cow}, volume = {77}, year = {2015} }