@article{oai:obihiro.repo.nii.ac.jp:00001083,
 author = {Miura, Saori and Horiuchi, Noriyuki and 堀内, 雅之 and Matsumoto, Kohtaro and 松本, 高太郎 and Kobayashi, Yoshiyasu and 古林, 与志安 and Kawazu, Shin-ichiro and 河津, 信一郎 and Inokuma, Hisashi and 猪熊, 壽},
 issue = {7},
 journal = {Journal of Veterinary Medical Science},
 month = {},
 note = {application/pdf, Monoclonal integration of bovine leukemia virus (BLV) proviral DNA into bovine genomes was detected in peripheral blood from two clinical cases of enzootic bovine leukosis (EBL) without enlargement of superficial lymph nodes. A BLV-specific probe hybridized with 1 to 3 EcoRI and HindIII fragments in these 2 atypical EBL cattle by Southern blotting and hybridization, as well as in 3 typical EBL cattle. The probe also hybridized to a large number of EcoRI and HindIII fragments in 5 cattle with persistent leukosis. These results suggest that the detection of monoclonal integration of BLV provirus into the host genome may serve as a marker of monoclonal proliferation and malignancy in difficult to diagnose EBL cattle.},
 pages = {883--887},
 title = {Detection of monoclonal integration of bovine leukemia virus proviral DNA as a malignant marker in two enzootic bovine leukosis cases with difficult clinical diagnosis},
 volume = {77},
 year = {2015}
}