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Changes in the Messenger RNA Expressions of the Endothelin-1 and Angiotensin Systems in Mature Follicles of the Superovulated Bovine Ovary
https://obihiro.repo.nii.ac.jp/records/466
https://obihiro.repo.nii.ac.jp/records/466fe159e0d-31e0-4d90-8cba-b8096c16cb31
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changesinthe.pdf (842.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2011-07-04 | |||||||||
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タイトル | Changes in the Messenger RNA Expressions of the Endothelin-1 and Angiotensin Systems in Mature Follicles of the Superovulated Bovine Ovary | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Angiotensin | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Bovine | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Endothelin-1 | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Gonadotrophin releasing hormone (GnRH) | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Ovulation | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
清水, 隆
× 清水, 隆× Berisha, Bajram× Schams, Dieter× 宮本, 明夫
WEKO
151
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内容記述タイプ | Abstract | |||||||||
内容記述 | The aim of the present study was to examine the messenger RNA expressions of the endothelin and angiotensin systems during the periovulatory phase in gonadotrophin releasing hormone (GnRH)-treated cows. Ovaries were collected by transvaginal ovariectomy (n=5 cows/group), and the follicles (n=5, one follicle/cow) were classified into the following groups: before GnRH administration (control, before LH surge), 3-5 h after GnRH (during LH surge), 10 h after GnRH; 20 h after GnRH, 25 h after GnRH (peri-ovulation), and early corpus luteum (CL) (Days 2-3). Expression of mRNA was investigated using quantitative real-time PCR. The expression of angiotensin converting enzyme (ACE) mRNA significantly decreased immediately after onset of the LH surge and remained at low levels. The levels of angiotensin II receptor type 1 (AT1R) and type 2 (AT2R) expression during the periovulatory period significantly decreased compared with other periods. The concentration of angiotensin II in follicular fluid began to increase 10 h after GnRH treatment and further increased as ovulation approached. The level of ET-1 mRNA significantly decreased 10 h after GnRH treatment compared with the levels before GnRH treatment and those of the early CL period. The expression of ETR-A and ETR-B mRNA during the periovulatory period were lower than in other periods. The expression of ECE-1 mRNA began to decrease in the LH surge period and significantly decrease in the periovulatory period compared with other periods. These results suggest that the vasoactive peptides angiotensin and endothelin may be associated with final maturation of follicles. | |||||||||
言語 | en | |||||||||
書誌情報 |
en : Journal of Reproduction and Development 巻 53, 号 3, p. 655-662, 発行日 2007 |
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出版者 | ||||||||||
出版者 | Japanese Society of Animal Reproduction | |||||||||
言語 | en | |||||||||
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収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 09168818 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA10936678 | |||||||||
DOI | ||||||||||
関連タイプ | isIdenticalTo | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | info:doi/10.1262/jrd.18168 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | Japanese Society of Animal Reproduction | |||||||||
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内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
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出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |