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Exposure to 50 Hz electric fields reduces stress-induced glucocorticoid levels in BALB/c mice in a kV/m- and duration-dependent manner
https://obihiro.repo.nii.ac.jp/records/4211
https://obihiro.repo.nii.ac.jp/records/42116aa0f86d-6370-4485-8cf3-938380c97b1d
名前 / ファイル | ライセンス | アクション |
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fulltext (327.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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公開日 | 2018-08-14 | |||||||||||||
タイトル | ||||||||||||||
言語 | en | |||||||||||||
タイトル | Exposure to 50 Hz electric fields reduces stress-induced glucocorticoid levels in BALB/c mice in a kV/m- and duration-dependent manner | |||||||||||||
言語 | ||||||||||||||
言語 | eng | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | ELF | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | dose-dependent | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | glucocorticoid | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | stress response | |||||||||||||
資源タイプ | ||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
資源タイプ | journal article | |||||||||||||
著者 |
Hori, Takuya
× Hori, Takuya× 井上, 昇
WEKO
63
× Suzuki, Hiroshi× 原川, 信二
WEKO
33
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抄録 | ||||||||||||||
内容記述タイプ | Abstract | |||||||||||||
内容記述 | Electric fields (EFs) can reduce elevated levels of stress-related hormones in some organisms. In this study, endocrine effects of exposure to a 50 Hz EF were investigated in male BALB/c mice. Specifically, plasma glucocorticoid (GC) levels were examined because GC is known to mediate the stress response in mice, including changes induced by immobilization. Mice were exposed to 50 Hz EFs (at 2.5-200 kV/m) for 60 min. They were immobilized for the latter half (30 min). At the end of exposure period, blood samples were collected and GC levels estimated by spectrofluorometry. GC levels were not influenced by EFs in absence of immobilization, but they were significantly higher in immobilized mice than in non-immobilized mice (P < 0.01). Elevated GC levels induced by immobilization were significantly reduced by exposure to an EF at 10 kV/m (P < 0.05), and the effect of EFs at 0-10 kV/m on GC levels increased in a kV/m-dependent manner (P < 0.05). In contrast, following treatment with EFs at 50 and 200 kV/m, GC levels were higher than those observed at 10 kV/m. To assess the effect of EF treatment duration, mice were also exposed to 50 Hz EFs (10 kV/m) for 6, 20, or 60 min. Immobilization-induced increase in GC levels was significantly suppressed by EF exposure for 20 and 60 min. Therefore, our results demonstrate that extremely low-frequency EFs alter stress response of mice in a kV/m- and duration-dependent manner. | |||||||||||||
言語 | en | |||||||||||||
書誌情報 |
en : Bioelectromagnetics 巻 36, 号 4, p. 302-308, 発行日 2015-05 |
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出版者 | ||||||||||||||
言語 | en | |||||||||||||
出版者 | Wiley Periodicals | |||||||||||||
ISSN | ||||||||||||||
収録物識別子タイプ | PISSN | |||||||||||||
収録物識別子 | 01978462 | |||||||||||||
書誌レコードID | ||||||||||||||
収録物識別子タイプ | NCID | |||||||||||||
収録物識別子 | AA00109934 | |||||||||||||
PubMed番号 | ||||||||||||||
関連タイプ | isVersionOf | |||||||||||||
識別子タイプ | PMID | |||||||||||||
関連識別子 | 25821169 | |||||||||||||
DOI | ||||||||||||||
関連タイプ | isVersionOf | |||||||||||||
識別子タイプ | DOI | |||||||||||||
関連識別子 | info:doi/10.1002/bem.21914 | |||||||||||||
フォーマット | ||||||||||||||
内容記述タイプ | Other | |||||||||||||
内容記述 | application/pdf | |||||||||||||
著者版フラグ | ||||||||||||||
出版タイプ | AM | |||||||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
日本十進分類法 | ||||||||||||||
主題Scheme | NDC | |||||||||||||
主題 | 427 |