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First clinical isolation report of azole-resistant Aspergillus fumigatus with TR34/L98H-type mutation in Japan
https://obihiro.repo.nii.ac.jp/records/4172
https://obihiro.repo.nii.ac.jp/records/41728738e0a4-a2df-4648-9816-cb16b78e4f79
名前 / ファイル | ライセンス | アクション |
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fulltext (334.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2018-03-07 | |||||||||
タイトル | ||||||||||
言語 | en | |||||||||
タイトル | First clinical isolation report of azole-resistant Aspergillus fumigatus with TR34/L98H-type mutation in Japan | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Aspergillus fumigatus | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Azole | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | cyp51A | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | TR34/L98H | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
豊留, 孝仁
× 豊留, 孝仁
WEKO
284
× Hagiwara, Daisuke× Kida, Hideyuki× Ogi, Takahiro× Watanabe, Akira× Wada, Terumi× Komatsu, Ryoichi× Kamei, Katsuhiko |
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | Recently, azole-resistant Aspergillus fumigatus containing a 34-bp or 46-bp tandem repeat in the promoter region of cyp51A combined with amino acid substitution(s) has appeared in the environment worldwide, including several Asian countries. In this study, we isolated the 34-bp tandem repeat-containing azole-resistant A. fumigatus strain OKH50 from a patient in Japan in May 2016. The patient had not been treated with medical azoles before the strain isolation, suggesting that the resistant property was acquired before infection. In addition, the patient had not traveled overseas. Our analysis of short tandem repeats of the strain indicates that the strain is strongly related to the 34-bp tandem repeat-containing isolates from European countries and Asia-Oceania countries but not to susceptible isolates from Japan, suggesting that the strain was introduced from overseas and might spread in Japan. c 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases | |||||||||
言語 | en | |||||||||
書誌情報 |
en : Journal of Infection and Chemotherapy 巻 23, 号 8, p. 579-581, 発行日 2017 |
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出版者 | ||||||||||
言語 | en | |||||||||
出版者 | Elsevier B.V. | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 1341321X | |||||||||
書誌レコードID | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA11057978 | |||||||||
DOI | ||||||||||
関連タイプ | isVersionOf | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | info:doi/10.1016/j.jiac.2016.12.004 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | This accepted manuscript is licensed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. <http://creativecommons.org/lisenses/by-nc-nd/4.0/> | |||||||||
フォーマット | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
著者版フラグ | ||||||||||
出版タイプ | AM | |||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
日本十進分類法 | ||||||||||
主題Scheme | NDC | |||||||||
主題 | 491 |