WEKO3
アイテム
{"_buckets": {"deposit": "2135df85-41b6-44cd-91a7-e929147d80a6"}, "_deposit": {"created_by": 12, "id": "317", "owners": [12], "pid": {"revision_id": 0, "type": "depid", "value": "317"}, "status": "published"}, "_oai": {"id": "oai:obihiro.repo.nii.ac.jp:00000317", "sets": ["5"]}, "author_link": ["334", "804", "132", "244", "337", "627", "151"], "item_2_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2005", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "489", "bibliographicPageStart": "483", "bibliographicVolumeNumber": "51", "bibliographic_titles": [{"bibliographic_title": "Journal of Reproduction and Development", "bibliographic_titleLang": "en"}]}]}, "item_2_description_19": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_2_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The aim of the present in vivo study was to monitor real-time fluctuations of cortisol (Cr) in the wall of preovulatory follicles using a microdialysis system (MDS) implanted in the theca layer as well as changes in ovarian venous plasma (OVP) and jugular venous plasma (JVP). Seven cows were superovulated using FSH and prostaglandin F2α injections. Dialysis capillary membranes were surgically implanted into the theca layer of mature follicles and connected to a microdialysis system. Fractions of the perfusates were collected from Day -1 (Day 0=LH surge) to Day 3. No difference in the concentrations of Cr between JVP and OVP was detected throughout the experiment. Circulating concentrations of Cr ranged from 20 to 35 ng/ml 8 h after surgery in ovulatory and anovulatory cows. In five ovulatory cows, the Cr concentration decreased to basal levels (\u003c10 ng/ml) between 12 and 24 h after surgery, however, two anovulatory cows retained high Cr levels (\u003e10 ng/ml) up to 42 h after surgery. There was a clear increase in the local concentration of Cr from 13.3 ± 2.1 pg/ml at -24 h to 27.5 ± 1.7 pg/ml at 0 h (peak of the LH surge) within the wall of ovulatory follicles. This increase was not detected in anovulatory follicles. This transient increase in Cr occurred only in the follicle wall, but not in the OVP or JVP, indicating that the presence of a local regulatory mechanism for Cr production/conversion in ovulatory follicles, and this mechanism may modulate the inflammatory-like reaction induced by LH surge in the follicle wall. The present results demonstrate that the glucocorticoid environment in the follicular wall adjusts at the local level in bovine ovulatory follicles. This mechanism may protect follicles from the adverse effects of glucocorticoid, and it may prevent excess inflammatory reactions associated with ovulation by temporarily increasing local concentrations of glucocorticoid, thus forming an integral part of the regulatory mechanism in ovarian physiology.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_2_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Japanese Society of Animal Reproduction", "subitem_publisher_language": "en"}]}, "item_2_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "info:doi/10.1262/jrd.17018", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Japanese Society of Animal Reproduction", "subitem_rights_language": "en"}]}, "item_2_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10936678", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "09168818", "subitem_source_identifier_type": "PISSN"}]}, "item_2_text_25": {"attribute_name": "文献提供者", "attribute_value_mlt": [{"subitem_text_value": "宮本明夫(akiomiya@obihiro.ac.jp)"}]}, "item_2_textarea_24": {"attribute_name": "作業記録", "attribute_value_mlt": [{"subitem_textarea_value": "Submitted by リポジトリ管理者 repo (repo@obihiro.ac.jp) on 2011-07-01T05:01:49Z\nNo. of bitstreams: 1\ninvivo.pdf: 634349 bytes, checksum: bb98ac00137d1c61e4f3a539ee107809 (MD5)"}, {"subitem_textarea_value": "Made available in DSpace on 2011-07-01T05:01:49Z (GMT). No. of bitstreams: 1\ninvivo.pdf: 634349 bytes, checksum: bb98ac00137d1c61e4f3a539ee107809 (MD5)\n Previous issue date: 2005"}]}, "item_2_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Acosta, Tomas J.", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "334", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002065458", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002065458"}, {"nameIdentifier": "80379718", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=80379718"}, {"nameIdentifier": "read0118629", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0118629"}]}, {"creatorNames": [{"creatorName": "Tetsuka, Masa", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "804", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsui, Motozumi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "132", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000001319718", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000001319718"}, {"nameIdentifier": "20374762", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=20374762"}, {"nameIdentifier": "read0202520", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0202520"}]}, {"creatorNames": [{"creatorName": "Shimizu, Takashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "244", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000001135036", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000001135036"}, {"nameIdentifier": "90375113", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=90375113"}]}, {"creatorNames": [{"creatorName": "Berisha, Bajram", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "337", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000007044301", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000007044301"}]}, {"creatorNames": [{"creatorName": "Schams, Dieter", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "627", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000007044302", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000007044302"}]}, {"creatorNames": [{"creatorName": "Miyamoto, Akio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "151", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000010192767", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/1000010192767"}, {"nameIdentifier": "10192767", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10192767"}, {"nameIdentifier": "read0167498", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0167498"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-01-30"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "invivo.pdf", "filesize": [{"value": "634.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 634300.0, "url": {"label": "invivo.pdf", "url": "https://obihiro.repo.nii.ac.jp/record/317/files/invivo.pdf"}, "version_id": "5f88da18-43bf-4e32-9c17-d124339d9fe6"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Bovine", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cortisol", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Follicle", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Ovary", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Ovulation", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "In Vivo Evidence that Local Cortisol Production Increases in the Preovulatory Follicle of the Cow", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "In Vivo Evidence that Local Cortisol Production Increases in the Preovulatory Follicle of the Cow", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "12", "path": ["5"], "permalink_uri": "https://obihiro.repo.nii.ac.jp/records/317", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2011-07-01"}, "publish_date": "2011-07-01", "publish_status": "0", "recid": "317", "relation": {}, "relation_version_is_last": true, "title": ["In Vivo Evidence that Local Cortisol Production Increases in the Preovulatory Follicle of the Cow"], "weko_shared_id": -1}
In Vivo Evidence that Local Cortisol Production Increases in the Preovulatory Follicle of the Cow
名前 / ファイル | ライセンス | アクション |
---|---|---|
invivo.pdf (634.3 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
公開日 | 2011-07-01 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | In Vivo Evidence that Local Cortisol Production Increases in the Preovulatory Follicle of the Cow | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Bovine | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Cortisol | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Follicle | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Ovary | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Ovulation | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
著者 |
Acosta, Tomas J.
× Acosta, Tomas J.
WEKO
334
× Tetsuka, Masa× Matsui, Motozumi
WEKO
132
× Shimizu, Takashi× Berisha, Bajram× Schams, Dieter× Miyamoto, Akio
WEKO
151
|
|||||||||||
抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | The aim of the present in vivo study was to monitor real-time fluctuations of cortisol (Cr) in the wall of preovulatory follicles using a microdialysis system (MDS) implanted in the theca layer as well as changes in ovarian venous plasma (OVP) and jugular venous plasma (JVP). Seven cows were superovulated using FSH and prostaglandin F2α injections. Dialysis capillary membranes were surgically implanted into the theca layer of mature follicles and connected to a microdialysis system. Fractions of the perfusates were collected from Day -1 (Day 0=LH surge) to Day 3. No difference in the concentrations of Cr between JVP and OVP was detected throughout the experiment. Circulating concentrations of Cr ranged from 20 to 35 ng/ml 8 h after surgery in ovulatory and anovulatory cows. In five ovulatory cows, the Cr concentration decreased to basal levels (<10 ng/ml) between 12 and 24 h after surgery, however, two anovulatory cows retained high Cr levels (>10 ng/ml) up to 42 h after surgery. There was a clear increase in the local concentration of Cr from 13.3 ± 2.1 pg/ml at -24 h to 27.5 ± 1.7 pg/ml at 0 h (peak of the LH surge) within the wall of ovulatory follicles. This increase was not detected in anovulatory follicles. This transient increase in Cr occurred only in the follicle wall, but not in the OVP or JVP, indicating that the presence of a local regulatory mechanism for Cr production/conversion in ovulatory follicles, and this mechanism may modulate the inflammatory-like reaction induced by LH surge in the follicle wall. The present results demonstrate that the glucocorticoid environment in the follicular wall adjusts at the local level in bovine ovulatory follicles. This mechanism may protect follicles from the adverse effects of glucocorticoid, and it may prevent excess inflammatory reactions associated with ovulation by temporarily increasing local concentrations of glucocorticoid, thus forming an integral part of the regulatory mechanism in ovarian physiology. | |||||||||||
言語 | en | |||||||||||
書誌情報 |
en : Journal of Reproduction and Development 巻 51, 号 4, p. 483-489, 発行日 2005 |
|||||||||||
出版者 | ||||||||||||
言語 | en | |||||||||||
出版者 | Japanese Society of Animal Reproduction | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | PISSN | |||||||||||
収録物識別子 | 09168818 | |||||||||||
書誌レコードID | ||||||||||||
収録物識別子タイプ | NCID | |||||||||||
収録物識別子 | AA10936678 | |||||||||||
DOI | ||||||||||||
関連タイプ | isIdenticalTo | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | info:doi/10.1262/jrd.17018 | |||||||||||
権利 | ||||||||||||
言語 | en | |||||||||||
権利情報 | Japanese Society of Animal Reproduction | |||||||||||
フォーマット | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | application/pdf | |||||||||||
著者版フラグ | ||||||||||||
出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |