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Proliferative Responses of T Subsets from Malaria-naive Human Donors [CD4+, CD8+, and Naive T Cell (CD45RA+)-enriched and Memory T Cell (CD45RO+)-enriched Subpopulations], to Plasmodium falciparum Polypeptide Antigens Isolated from the Merozoite Stage
https://obihiro.repo.nii.ac.jp/records/1717
https://obihiro.repo.nii.ac.jp/records/171727f13a70-e99a-4791-a373-d3ff9fde6ce4
名前 / ファイル | ライセンス | アクション |
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Prot.Vol.2-2-2.pdf (546.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2006-12-21 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Proliferative Responses of T Subsets from Malaria-naive Human Donors [CD4+, CD8+, and Naive T Cell (CD45RA+)-enriched and Memory T Cell (CD45RO+)-enriched Subpopulations], to Plasmodium falciparum Polypeptide Antigens Isolated from the Merozoite Stage | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Plasmodium falciparum | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | proliferative response | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | T subsets | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | merozoite antigens | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Goerlich, Roland
× Goerlich, Roland× Heidrich, Hans-G. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Mononuclear cells, CD2+ T cells and T subsets (CD4+, CD8+) from HLA-typed malaria-naive donors were stimulated with isolated surface antigens (Ags) from Plasmodium falciparum merozoites (MSP183, MSP136, MSP2). Cell responses in lymphocyte proliferation assays were MHC-class II and mainly DR restricted. Donors could be grouped into high, non or low responders according to the proliferative response. The high responders possessed the combination DR7/DRw53 as a common HLA-restriction element. Non and low responders did not have this Ag combination, but some were characterized by DQwl. Individual donors did not show any Ag dependent response. CD45RA+ (naive, non-stimulated) enriched T cells from high-responders were strongly stimulated by the merozoite Ags, whereas stimulation of CD45RO+ (memory) enriched T cells was much lower. | |||||
言語 | en | |||||
書誌情報 |
en : The journal of protozoology research 巻 2, 号 2, p. 53-67, 発行日 1992-04 |
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出版者 | ||||||
言語 | en | |||||
出版者 | Research Center for Protozoan Molecular Immunology | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 09174427 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10824856 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | Research Center for Protozoan Molecular Immunology | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
言語 | en | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 649 |