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Construction of the recombinant pseudorabies viruses expressing Cryptosporidium parvum an immunodominant surface protein, p23
https://obihiro.repo.nii.ac.jp/records/1537
https://obihiro.repo.nii.ac.jp/records/1537fca0eaed-9b33-4d2c-863b-423342be0db4
名前 / ファイル | ライセンス | アクション |
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Prot.Vol.10-4-1.pdf (88.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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公開日 | 2006-12-19 | |||||||||||||
タイトル | ||||||||||||||
言語 | en | |||||||||||||
タイトル | Construction of the recombinant pseudorabies viruses expressing Cryptosporidium parvum an immunodominant surface protein, p23 | |||||||||||||
言語 | ||||||||||||||
言語 | eng | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | Cryptosporidium parvum | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | p23 | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | herpes | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | pseudorabies virus | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | subunit vaccine | |||||||||||||
資源タイプ | ||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
資源タイプ | journal article | |||||||||||||
著者 |
Takashima, Yasuhiro
× Takashima, Yasuhiro× 玄, 学南
WEKO
295
× Nagasawa, Hideyuki× Matsumoto, Yasunobu× 五十嵐, 郁男
WEKO
58
× Fujisaki, Kozo× Mikami, Takeshi× Otsuka, Haruki |
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抄録 | ||||||||||||||
内容記述タイプ | Abstract | |||||||||||||
内容記述 | To develop a vaccine against cryptosporidiosis in animals, we constructed recombinant pseudorabies virus (PrV), a member of the Herpesviridae Alphaherpesvirus subfamily, expressing an immunodominant surface protein p23 of Cryptosporidium parvum sporozoites. Because of the wide host range of PrV, it has the possibility as the vector to delivery the foreign genes to several species of animals containing experiment animal. In the recombinant constructed in this study, the p23 gene under the control of CAG promoter was integrated into the thymidine kinase (TK) gene of PRV. Antibody against p23 recognized p23 expressed in CPK cells infected with the recombinant, as the approximate 23 kDa specific band in Western blotting analysis. This study showed the possibility of a PrV recombinant as a vaccine against cryptosporidiosis in animals. | |||||||||||||
言語 | en | |||||||||||||
書誌情報 |
en : The journal of protozoology research 巻 10, 号 4, p. 173-179, 発行日 2000-10 |
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出版者 | ||||||||||||||
言語 | en | |||||||||||||
出版者 | National Research Center for Protozoan Diseases | |||||||||||||
ISSN | ||||||||||||||
収録物識別子タイプ | PISSN | |||||||||||||
収録物識別子 | 09174427 | |||||||||||||
書誌レコードID | ||||||||||||||
収録物識別子タイプ | NCID | |||||||||||||
収録物識別子 | AA10824856 | |||||||||||||
権利 | ||||||||||||||
言語 | en | |||||||||||||
権利情報 | National Research Center for Protozoan Diseases | |||||||||||||
フォーマット | ||||||||||||||
内容記述タイプ | Other | |||||||||||||
内容記述 | application/pdf | |||||||||||||
著者版フラグ | ||||||||||||||
出版タイプ | VoR | |||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
日本十進分類法 | ||||||||||||||
主題Scheme | NDC | |||||||||||||
主題 | 649 |