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DNA vaccine coding a p23 protein of Cryptosporidium parvum fused with Fc portion of immunogloblin G induces higher level of interferon-γ expression in mice
https://obihiro.repo.nii.ac.jp/records/1502
https://obihiro.repo.nii.ac.jp/records/150256c0c604-3cdd-4be8-a6d3-4cc88a14e410
名前 / ファイル | ライセンス | アクション |
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Prot.Vol15-(3).pdf (132.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2006-12-20 | |||||||||
タイトル | ||||||||||
言語 | en | |||||||||
タイトル | DNA vaccine coding a p23 protein of Cryptosporidium parvum fused with Fc portion of immunogloblin G induces higher level of interferon-γ expression in mice | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | C. parvum | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | DNA vaccine | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Fc | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Interferon-8 | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
Takashima, Yasuhiro
× Takashima, Yasuhiro× 玄, 学南
WEKO
295
× Shirafuji, Hiroaki× Zhang, Guohong× Otsuka, Haruki |
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | To develop DNA vaccines against Cryptosporidiosis, a plasmid coding an immunodominant protein of Cryptosporidium parvum sporozoite, p23 (pCX-p23) and another plasmid coding a fusion protein containing whole the p23 and the Fc portion of mouse immunogloblin G1 (pCX-p23Fc). Vaccination of BALB/c mice with the plasmid, pCX-p23 and pCX-p23Fc induced the production of antibodies against p23. Although both of splenocytes of mice immunized with the plasmids pCX-p23 and pCX-p23Fc expressed interleukin-4 and interferon-8, after the in vitro stimulation by p23 antigen, the interferon-8 expression level of pCX-p23Fc immunized mice was much higher than that of pCX-p23 immunized mice. These results suggest a possibility of the plasmid pCX-p23Fc as a DNA vaccine candidate against cryptosporidiosis. | |||||||||
言語 | en | |||||||||
書誌情報 |
en : The journal of protozoology research 巻 15, 号 1-2, p. 14-19, 発行日 2005-04 |
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出版者 | ||||||||||
言語 | en | |||||||||
出版者 | National Research Center for Protozoan Diseases | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 09174427 | |||||||||
書誌レコードID | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA10824856 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | National Research Center for Protozoan Diseases | |||||||||
フォーマット | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
著者版フラグ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
日本十進分類法 | ||||||||||
主題Scheme | NDC | |||||||||
主題 | 649 |