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Exposure to 50-Hz electric fields on stress response initiated by infection with the protozoan parasite, Toxoplasma gondii, in mice
https://obihiro.repo.nii.ac.jp/records/1490
https://obihiro.repo.nii.ac.jp/records/1490d8675a07-6c89-4e51-b3e2-83ed5565bcd3
名前 / ファイル | ライセンス | アクション |
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v16-3,4-3.pdf (73.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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公開日 | 2007-05-24 | |||||||||||||
タイトル | ||||||||||||||
言語 | en | |||||||||||||
タイトル | Exposure to 50-Hz electric fields on stress response initiated by infection with the protozoan parasite, Toxoplasma gondii, in mice | |||||||||||||
言語 | ||||||||||||||
言語 | eng | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | 50-Hz | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | electric field | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | Hsp-60 | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | stress response | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | survival rate | |||||||||||||
資源タイプ | ||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
資源タイプ | journal article | |||||||||||||
著者 |
Hori, Takuya
× Hori, Takuya× 原川, 信二
WEKO
33
× 井上, 昇
WEKO
63
× Nagasawa, Hideyuki× Kariya, Tatsuya |
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抄録 | ||||||||||||||
内容記述タイプ | Abstract | |||||||||||||
内容記述 | The present study was aimed to examine whether a 50-Hz electric field (EF) affects biological stress responses. Male C57BL/6J mice were exposed to either 50-Hz EF (45 kV/m) or given a sham exposure for 30 minutes per day for 1, 2 or 4 weeks and then either mock inoculated or inoculated with the protozoan parasite, Toxoplasma gondii (T. gondii) PLK strain. Survival rate was calculated in mice infected with T. gondii after exposure to EF and the serum antibody levels to heat shock protein 60 (Hsp-60), and mRNA levels for Hsp-60, IFN-γ and IL-12p35 in mouse peripheral leucocytes were determined. As a result, no statistically significant difference was found in survival rate between mice exposed to EF and those in the sham exposure group. When mice were inoculated with T. gondii, plasma level of anti-Hsp-60 antibody increased gradually until day 16 after inoculation and remained at an elevated value until the end of the experimental period. On day 2 and 9 after inoculation, the increment in anti-Hsp-60 antibody level was significantly suppressed in mice exposed to EF as compared to those in the sham exposure group (p<0.05). Differences in changes in mRNA levels in Hsp-60, IFN- γ and IL-12p35 were not statistically significant. Taken together, our findings indicate that exposure to 50-Hz EF does not affect viability of mice infected with T. gondii but seems to slightly play inhibitory on the early phase of stress responses. | |||||||||||||
言語 | en | |||||||||||||
書誌情報 |
en : The journal of protozoology research 巻 16, 号 3-4, p. 51-59, 発行日 2006-10 |
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出版者 | ||||||||||||||
言語 | en | |||||||||||||
出版者 | National Research Center for Protozoan Diseases | |||||||||||||
ISSN | ||||||||||||||
収録物識別子タイプ | PISSN | |||||||||||||
収録物識別子 | 09174427 | |||||||||||||
書誌レコードID | ||||||||||||||
収録物識別子タイプ | NCID | |||||||||||||
収録物識別子 | AA10824856 | |||||||||||||
フォーマット | ||||||||||||||
内容記述タイプ | Other | |||||||||||||
内容記述 | application/pdf | |||||||||||||
著者版フラグ | ||||||||||||||
出版タイプ | VoR | |||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
日本十進分類法 | ||||||||||||||
主題Scheme | NDC | |||||||||||||
主題 | 649 |