WEKO3
アイテム
{"_buckets": {"deposit": "d0d81ca4-07ba-45f1-92cf-18c657d10783"}, "_deposit": {"created_by": 12, "id": "1485", "owners": [12], "pid": {"revision_id": 0, "type": "depid", "value": "1485"}, "status": "published"}, "_oai": {"id": "oai:obihiro.repo.nii.ac.jp:00001485", "sets": ["24"]}, "author_link": ["58", "3169", "1117", "295", "3172", "3170", "3174", "345", "63", "312", "3171"], "item_2_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "15", "bibliographicPageStart": "9", "bibliographicVolumeNumber": "17", "bibliographic_titles": [{"bibliographic_title": "The journal of protozoology research", "bibliographic_titleLang": "en"}]}]}, "item_2_description_19": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_2_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The oligomannose-coated liposome (OML) vaccine is known to induce cellular immunity specific for the encapsulated antigen in immunized mice. In the present study, we preliminarily evaluated the effect of the OML vaccine encapsulating the soluble protozoan lysate of Toxoplasma gondii, Trypanosoma brucei gambiense, or Babesia rodhaini on the corresponding protozoan infections in mice. After the challenge of T. gondii, the OML vaccine group avoided the high mortality resulting from acute infection that was dominantly observed in other control groups. During the infectious course, the development of the T. gondii-specific antibody, which is an indicator of humoral immunity, was constantly controlled at a lower level in the surviving mice of the OML vaccine group than in other lethally affected mice. On the other hand, other OML vaccines targeting for T. b. gambiense and B. rodhaini did not show any effect on these lethal infections in mice. The present preliminary study suggests that OML is a novel vaccine tool, at least for the control of acute toxoplasmosis.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_2_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "National Research Center for Protozoan Diseases", "subitem_publisher_language": "en"}]}, "item_2_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "National Research Center for Protozoan Diseases", "subitem_rights_language": "en"}]}, "item_2_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10824856", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "09174427", "subitem_source_identifier_type": "PISSN"}]}, "item_2_subject_21": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "649", "subitem_subject_scheme": "NDC"}]}, "item_2_textarea_24": {"attribute_name": "作業記録", "attribute_value_mlt": [{"subitem_textarea_value": "Submitted by リポジトリ管理者 repo (repo@obihiro.ac.jp) on 2007-07-26T07:34:19Z\nNo. of bitstreams: 1\nv17-1-2.PDF: 2556818 bytes, checksum: 94ef547bbb182f46114ac4ed682bc451 (MD5)"}, {"subitem_textarea_value": "Made available in DSpace on 2007-07-26T07:34:20Z (GMT). No. of bitstreams: 1\nv17-1-2.PDF: 2556818 bytes, checksum: 94ef547bbb182f46114ac4ed682bc451 (MD5)\n Previous issue date: 2007-06"}]}, "item_2_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kuboki, Noritaka", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "345", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000005764978", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000005764978"}]}, {"creatorNames": [{"creatorName": "Tiwananthagorn, Weerawan", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3169", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takagi, Hideaki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3170", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakayama, Tomoko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3171", "nameIdentifierScheme": "WEKO"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "Xuan, Xuenan", "creatorNameLang": "en"}, {"creatorName": "玄, 学南", "creatorNameLang": "ja"}], "familyNames": [{"familyName": "Xuan", "familyNameLang": "en"}, {"familyName": "玄", "familyNameLang": "ja"}], "givenNames": [{"givenName": "Xuenan", "givenNameLang": "en"}, {"givenName": "学南", "givenNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "295", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002841347", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002841347"}, {"nameIdentifier": "10292096", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10292096"}, {"nameIdentifier": "read0055834", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0055834"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "Inoue, Noboru", "creatorNameLang": "en"}, {"creatorName": "井上, 昇", "creatorNameLang": "ja"}], "familyNames": [{"familyName": "Inoue", "familyNameLang": "en"}, {"familyName": "井上", "familyNameLang": "ja"}], "givenNames": [{"givenName": "Noboru", "givenNameLang": "en"}, {"givenName": "昇", "givenNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "63", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002841346", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002841346"}, {"nameIdentifier": "10271751", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10271751"}, {"nameIdentifier": "read0185948", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0185948"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "Igarashi, Ikuo", "creatorNameLang": "en"}, {"creatorName": "五十嵐, 郁男", "creatorNameLang": "ja"}], "familyNames": [{"familyName": "Igarashi", "familyNameLang": "en"}, {"familyName": "五十嵐", "familyNameLang": "ja"}], "givenNames": [{"givenName": "Ikuo", "givenNameLang": "en"}, {"givenName": "郁男", "givenNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "58", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000003078567", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000003078567"}, {"nameIdentifier": "80159582", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=80159582"}, {"nameIdentifier": "read0167555", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0167555"}]}, {"creatorNames": [{"creatorName": "Tsujimura, Kunio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3172", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ikehara, Yuzuru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1117", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kojima, Naoya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3174", "nameIdentifierScheme": "WEKO"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "Yokoyama, Naoaki", "creatorNameLang": "en"}, {"creatorName": "横山, 直明", "creatorNameLang": "ja"}], "familyNames": [{"familyName": "Yokoyama", "familyNameLang": "en"}, {"familyName": "横山", "familyNameLang": "ja"}], "givenNames": [{"givenName": "Naoaki", "givenNameLang": "en"}, {"givenName": "直明", "givenNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "312", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002627114", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002627114"}, {"nameIdentifier": "80301802", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=80301802"}, {"nameIdentifier": "read0074761", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0074761"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-01-30"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "v17-1-2.PDF", "filesize": [{"value": "2.6 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 2600000.0, "url": {"label": "v17-1-2.PDF", "url": "https://obihiro.repo.nii.ac.jp/record/1485/files/v17-1-2.PDF"}, "version_id": "eb99c22c-8053-47ef-817e-77ac25ae30b0"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "oligomannose-coated liposome (OML)", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "OML", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "soluble protozoan antigen", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "antibody responses", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Preliminary evaluation of oligomannose-coated liposome vaccines against lethal protozoan infections in mice", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Preliminary evaluation of oligomannose-coated liposome vaccines against lethal protozoan infections in mice", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "12", "path": ["24"], "permalink_uri": "https://obihiro.repo.nii.ac.jp/records/1485", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-07-26"}, "publish_date": "2007-07-26", "publish_status": "0", "recid": "1485", "relation": {}, "relation_version_is_last": true, "title": ["Preliminary evaluation of oligomannose-coated liposome vaccines against lethal protozoan infections in mice"], "weko_shared_id": -1}
Preliminary evaluation of oligomannose-coated liposome vaccines against lethal protozoan infections in mice
名前 / ファイル | ライセンス | アクション |
---|---|---|
v17-1-2.PDF (2.6 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
公開日 | 2007-07-26 | |||||||||||||||||||||
タイトル | ||||||||||||||||||||||
言語 | en | |||||||||||||||||||||
タイトル | Preliminary evaluation of oligomannose-coated liposome vaccines against lethal protozoan infections in mice | |||||||||||||||||||||
言語 | ||||||||||||||||||||||
言語 | eng | |||||||||||||||||||||
キーワード | ||||||||||||||||||||||
言語 | en | |||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||
主題 | oligomannose-coated liposome (OML) | |||||||||||||||||||||
キーワード | ||||||||||||||||||||||
言語 | en | |||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||
主題 | OML | |||||||||||||||||||||
キーワード | ||||||||||||||||||||||
言語 | en | |||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||
主題 | soluble protozoan antigen | |||||||||||||||||||||
キーワード | ||||||||||||||||||||||
言語 | en | |||||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||||
主題 | antibody responses | |||||||||||||||||||||
資源タイプ | ||||||||||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
資源タイプ | journal article | |||||||||||||||||||||
著者 |
Kuboki, Noritaka
× Kuboki, Noritaka× Tiwananthagorn, Weerawan× Takagi, Hideaki× Nakayama, Tomoko× 玄, 学南
WEKO
295
× 井上, 昇
WEKO
63
× 五十嵐, 郁男
WEKO
58
× Tsujimura, Kunio× Ikehara, Yuzuru× Kojima, Naoya× 横山, 直明
WEKO
312
|
|||||||||||||||||||||
抄録 | ||||||||||||||||||||||
内容記述タイプ | Abstract | |||||||||||||||||||||
内容記述 | The oligomannose-coated liposome (OML) vaccine is known to induce cellular immunity specific for the encapsulated antigen in immunized mice. In the present study, we preliminarily evaluated the effect of the OML vaccine encapsulating the soluble protozoan lysate of Toxoplasma gondii, Trypanosoma brucei gambiense, or Babesia rodhaini on the corresponding protozoan infections in mice. After the challenge of T. gondii, the OML vaccine group avoided the high mortality resulting from acute infection that was dominantly observed in other control groups. During the infectious course, the development of the T. gondii-specific antibody, which is an indicator of humoral immunity, was constantly controlled at a lower level in the surviving mice of the OML vaccine group than in other lethally affected mice. On the other hand, other OML vaccines targeting for T. b. gambiense and B. rodhaini did not show any effect on these lethal infections in mice. The present preliminary study suggests that OML is a novel vaccine tool, at least for the control of acute toxoplasmosis. | |||||||||||||||||||||
言語 | en | |||||||||||||||||||||
書誌情報 |
en : The journal of protozoology research 巻 17, 号 1, p. 9-15, 発行日 2007-06 |
|||||||||||||||||||||
出版者 | ||||||||||||||||||||||
言語 | en | |||||||||||||||||||||
出版者 | National Research Center for Protozoan Diseases | |||||||||||||||||||||
ISSN | ||||||||||||||||||||||
収録物識別子タイプ | PISSN | |||||||||||||||||||||
収録物識別子 | 09174427 | |||||||||||||||||||||
書誌レコードID | ||||||||||||||||||||||
収録物識別子タイプ | NCID | |||||||||||||||||||||
収録物識別子 | AA10824856 | |||||||||||||||||||||
権利 | ||||||||||||||||||||||
言語 | en | |||||||||||||||||||||
権利情報 | National Research Center for Protozoan Diseases | |||||||||||||||||||||
フォーマット | ||||||||||||||||||||||
内容記述タイプ | Other | |||||||||||||||||||||
内容記述 | application/pdf | |||||||||||||||||||||
著者版フラグ | ||||||||||||||||||||||
出版タイプ | VoR | |||||||||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||
日本十進分類法 | ||||||||||||||||||||||
主題Scheme | NDC | |||||||||||||||||||||
主題 | 649 |