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An autoregressive logistic model to predict the reciprocal effects of oviductal fluid components on in vitro spermophagy by neutrophils in cattle
https://obihiro.repo.nii.ac.jp/records/1264
https://obihiro.repo.nii.ac.jp/records/12642744f2af-959d-441c-8593-199d7914c643
名前 / ファイル | ライセンス | アクション |
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s41598-017-04841-z.pdf (2.1 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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公開日 | 2017-08-24 | |||||||
タイトル | ||||||||
言語 | en | |||||||
タイトル | An autoregressive logistic model to predict the reciprocal effects of oviductal fluid components on in vitro spermophagy by neutrophils in cattle | |||||||
言語 | ||||||||
言語 | eng | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | journal article | |||||||
著者 |
Kowsar, Rasoul
× Kowsar, Rasoul× Keshtegar, Behrooz× Marey, Mohamed. A.× Miyamoto, Akio
WEKO
151
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抄録 | ||||||||
内容記述タイプ | Abstract | |||||||
内容記述 | After intercourse/insemination, large numbers of sperm are deposited in the female reproductive tract (FRT), triggering a massive recruitment of neutrophils (PMNs) into the FRT, possibly to eliminate excessive sperm via phagocytosis. Some bovine oviductal fluid components (BOFCs) have been shown to regulate in vitro sperm phagocytosis (spermophagy) by PMNs. The modeling approach-based logistic regression (LR) and autoregressive logistic regression (ALR) can be used to predict the behavior of complex biological systems. We, first, compared the LR and ALR models using in vitro data to find which of them provides a better prediction of in vitro spermophagy in bovine. Then, the best model was used to identify and classify the reciprocal effects of BOFCs in regulating spermophagy. The ALR model was calibrated using an iterative procedure with a dynamical search direction. The superoxide production data were used to illustrate the accuracy in validating logit model-based ALR and LR. The ALR model was more accurate than the LR model. Based on in vitro data, the ALR predicted that the regulation of spermophagy by PMNs in bovine oviduct is more sensitive to alpha-1 acid glycoprotein (AGP), PGE2, bovine serum albumin (BSA), and to the combination of AGP or BSA with other BOFCs. | |||||||
言語 | en | |||||||
書誌情報 |
en : Scientific Reports 巻 7, p. 4482, 発行日 2017-01-30 |
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出版者 | ||||||||
言語 | en | |||||||
出版者 | Nature Publishing Group | |||||||
ISSN | ||||||||
収録物識別子タイプ | PISSN | |||||||
収録物識別子 | 20452322 | |||||||
DOI | ||||||||
関連タイプ | isIdenticalTo | |||||||
識別子タイプ | DOI | |||||||
関連識別子 | info:doi/10.1038/s41598-017-04841-z | |||||||
権利 | ||||||||
言語 | en | |||||||
権利情報 | This is an open access article licensed under the terms of the Creative Commons Attribution (by) License. <http://creativecommons.org/lisenses/by/4.0/> | |||||||
フォーマット | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | application/pdf | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
日本十進分類法 | ||||||||
主題Scheme | NDC | |||||||
主題 | 648 |