WEKO3
アイテム
{"_buckets": {"deposit": "d9eaf231-1d2e-477e-a020-d67dcafaa62e"}, "_deposit": {"created_by": 12, "id": "1211", "owners": [12], "pid": {"revision_id": 0, "type": "depid", "value": "1211"}, "status": "published"}, "_oai": {"id": "oai:obihiro.repo.nii.ac.jp:00001211", "sets": ["5"]}, "author_link": ["2538", "2536", "330", "2537", "2535", "357", "394", "63", "2539"], "item_2_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "4393", "bibliographicPageStart": "4391", "bibliographicVolumeNumber": "60", "bibliographic_titles": [{"bibliographic_title": "Antimicrobial Agents and Chemotherapy", "bibliographic_titleLang": "en"}]}]}, "item_2_description_19": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_2_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "This study aimed to evaluate the trypanocidal activity of mycophenolic acid (MPA) and its derivatives for Trypanosoma congolense. The proliferation of T. congolense was completely inhibited by adding \u003c1 mu M MPA and its derivatives. In addition, the IMP dehydrogenase in T. congolense was molecularly characterized as the target of these compounds. The results suggest that MPA and its derivatives have the potential to be new candidates as novel trypanocidal drugs.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_2_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "American Society for Microbiology", "subitem_publisher_language": "en"}]}, "item_2_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "info:doi/10.1128/AAC.02816-15", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "American Society for Microbiology", "subitem_rights_language": "en"}]}, "item_2_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00542574", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00664804", "subitem_source_identifier_type": "PISSN"}]}, "item_2_subject_21": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "491.7", "subitem_subject_scheme": "NDC"}]}, "item_2_text_25": {"attribute_name": "文献提供者", "attribute_value_mlt": [{"subitem_text_value": "菅沼啓輔(k.suganuma@obihiro.ac.jp)"}]}, "item_2_textarea_24": {"attribute_name": "作業記録", "attribute_value_mlt": [{"subitem_textarea_value": "Submitted by リポジトリ管理者 repo (repo@obihiro.ac.jp) on 2017-09-07T23:49:39Z\nNo. of bitstreams: 1\nSuganuma et al.pdf: 543990 bytes, checksum: fe8a78ab810cea0c88403c20ff2534aa (MD5)"}, {"subitem_textarea_value": "Made available in DSpace on 2017-09-07T23:49:39Z (GMT). No. of bitstreams: 1\nSuganuma et al.pdf: 543990 bytes, checksum: fe8a78ab810cea0c88403c20ff2534aa (MD5)\n Previous issue date: 2016-07"}]}, "item_2_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "Suganuma, Keisuke", "creatorNameLang": "en"}, {"creatorName": "菅沼, 啓輔", "creatorNameLang": "ja"}], "familyNames": [{"familyName": "Suganuma", "familyNameLang": "en"}, {"familyName": "菅沼", "familyNameLang": "ja"}], "givenNames": [{"givenName": "Keisuke", "givenNameLang": "en"}, {"givenName": "啓輔", "givenNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "357", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000345306716", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000345306716"}, {"nameIdentifier": "60772184", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60772184"}, {"nameIdentifier": "11922960", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/11922960"}]}, {"creatorNames": [{"creatorName": "Sarwono, Albertus Eka Yudistira", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2535", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mitsuhashi, Shinya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2536", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Jąkalski, Marcin", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2537", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okada, Tadashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "394", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "30623855", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=30623855"}]}, {"creatorNames": [{"creatorName": "Nthatisi, Molefe", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2538", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamagishi, Junya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "330", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000363269204", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000363269204"}, {"nameIdentifier": "80535328", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=80535328"}, {"nameIdentifier": "j1234567890", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/j1234567890"}]}, {"creatorNames": [{"creatorName": "Ubukata, Makoto", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "2539", "nameIdentifierScheme": "WEKO"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "Inoue, Noboru", "creatorNameLang": "en"}, {"creatorName": "井上, 昇", "creatorNameLang": "ja"}], "familyNames": [{"familyName": "Inoue", "familyNameLang": "en"}, {"familyName": "井上", "familyNameLang": "ja"}], "givenNames": [{"givenName": "Noboru", "givenNameLang": "en"}, {"givenName": "昇", "givenNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "63", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000002841346", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000002841346"}, {"nameIdentifier": "10271751", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10271751"}, {"nameIdentifier": "read0185948", "nameIdentifierScheme": "researchmap", "nameIdentifierURI": "https://researchmap.jp/read0185948"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-01-30"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Suganuma et al.pdf", "filesize": [{"value": "544.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 544000.0, "url": {"label": "Suganuma et al.pdf", "url": "https://obihiro.repo.nii.ac.jp/record/1211/files/Suganuma et al.pdf"}, "version_id": "7b9f8a89-bc14-45d4-b675-bfbef310c45b"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Mycophenolic acid and its derivatives as potential chemotherapeutic agents targeting inosine monophosphate dehydrogenase in Trypanosoma congolense", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Mycophenolic acid and its derivatives as potential chemotherapeutic agents targeting inosine monophosphate dehydrogenase in Trypanosoma congolense", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "12", "path": ["5"], "permalink_uri": "https://obihiro.repo.nii.ac.jp/records/1211", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2017-09-07"}, "publish_date": "2017-09-07", "publish_status": "0", "recid": "1211", "relation": {}, "relation_version_is_last": true, "title": ["Mycophenolic acid and its derivatives as potential chemotherapeutic agents targeting inosine monophosphate dehydrogenase in Trypanosoma congolense"], "weko_shared_id": -1}
Mycophenolic acid and its derivatives as potential chemotherapeutic agents targeting inosine monophosphate dehydrogenase in Trypanosoma congolense
名前 / ファイル | ライセンス | アクション |
---|---|---|
Suganuma et al.pdf (544.0 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
公開日 | 2017-09-07 | |||||||||||||||
タイトル | ||||||||||||||||
言語 | en | |||||||||||||||
タイトル | Mycophenolic acid and its derivatives as potential chemotherapeutic agents targeting inosine monophosphate dehydrogenase in Trypanosoma congolense | |||||||||||||||
言語 | ||||||||||||||||
言語 | eng | |||||||||||||||
資源タイプ | ||||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
資源タイプ | journal article | |||||||||||||||
著者 |
菅沼, 啓輔
× 菅沼, 啓輔
WEKO
357
× Sarwono, Albertus Eka Yudistira× Mitsuhashi, Shinya× Jąkalski, Marcin× Okada, Tadashi× Nthatisi, Molefe× Yamagishi, Junya
WEKO
330
× Ubukata, Makoto× 井上, 昇
WEKO
63
|
|||||||||||||||
抄録 | ||||||||||||||||
内容記述タイプ | Abstract | |||||||||||||||
内容記述 | This study aimed to evaluate the trypanocidal activity of mycophenolic acid (MPA) and its derivatives for Trypanosoma congolense. The proliferation of T. congolense was completely inhibited by adding <1 mu M MPA and its derivatives. In addition, the IMP dehydrogenase in T. congolense was molecularly characterized as the target of these compounds. The results suggest that MPA and its derivatives have the potential to be new candidates as novel trypanocidal drugs. | |||||||||||||||
言語 | en | |||||||||||||||
書誌情報 |
en : Antimicrobial Agents and Chemotherapy 巻 60, 号 7, p. 4391-4393, 発行日 2016-07 |
|||||||||||||||
出版者 | ||||||||||||||||
言語 | en | |||||||||||||||
出版者 | American Society for Microbiology | |||||||||||||||
ISSN | ||||||||||||||||
収録物識別子タイプ | PISSN | |||||||||||||||
収録物識別子 | 00664804 | |||||||||||||||
書誌レコードID | ||||||||||||||||
収録物識別子タイプ | NCID | |||||||||||||||
収録物識別子 | AA00542574 | |||||||||||||||
DOI | ||||||||||||||||
関連タイプ | isVersionOf | |||||||||||||||
識別子タイプ | DOI | |||||||||||||||
関連識別子 | info:doi/10.1128/AAC.02816-15 | |||||||||||||||
権利 | ||||||||||||||||
言語 | en | |||||||||||||||
権利情報 | American Society for Microbiology | |||||||||||||||
フォーマット | ||||||||||||||||
内容記述タイプ | Other | |||||||||||||||
内容記述 | application/pdf | |||||||||||||||
著者版フラグ | ||||||||||||||||
出版タイプ | AM | |||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||
日本十進分類法 | ||||||||||||||||
主題Scheme | NDC | |||||||||||||||
主題 | 491.7 |