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Genetic characterization of H5N2 influenza viruses isolated from wild birds in Japan suggests multiple reassortment
https://obihiro.repo.nii.ac.jp/records/1185
https://obihiro.repo.nii.ac.jp/records/11853110a438-8bf9-46e4-b19e-a54d87673237
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Arch Virol (2016) 161 3309.pdf (2.2 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2017-12-04 | |||||||
| タイトル | ||||||||
| タイトル | Genetic characterization of H5N2 influenza viruses isolated from wild birds in Japan suggests multiple reassortment | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
Sultan, Serageldeen
× Sultan, Serageldeen× Vuong, Nghia Bui× Hill, Nichola J.× Hussein, Islam T. M.× Dai, Quang Trinh× Inage, Kumiko× Hashizume, Taishi× Runstadler, Jonathan A.× 小川, 晴子× Imai, Kunitoshi
WEKO
328
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| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Low-pathogenic avian influenza viruses (LPAIVs) of the H5 subtype can mutate to highly pathogenic forms, potentially destabilizing the poultry industry. Wild migratory birds are considered a natural reservoir of LPAIVs capable of dispersing both high- and low-pathogenic forms of the virus. Therefore, surveillance and characterization of AIV in wild birds are essential. Here, we report on the isolation and genetic characterization of 10 AIVs of the H5N2 subtype obtained through surveillance in Hokkaido, Japan, during 2009 and 2011. Full-genome sequencing revealed that the H5 and N2 genes of these isolates are all closely related to each other, belonging to the Eurasian avian-like lineage, but they are unrelated to H5 highly pathogenic strains of clade 2.3.4.4. The internal genes of the isolates were found to be diverse, consistent with our hypothesis that these H5N2 strains have undergone multiple reassortment events. Even though all of the H5N2 isolates were characterized as LPAIV based on the amino acid sequences at the HA cleavage site, this analysis demonstrates a diverse pool of precursors that may seed future outbreaks in poultry and possible human transmissions, suggesting the need for high-quality surveillance. | |||||||
| 書誌情報 |
en : Archives of Virology 巻 161, 号 12, p. 3309-3322, 発行日 2016 |
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| 出版者 | ||||||||
| 出版者 | Springer | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 03048608 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00548901 | |||||||
| DOI | ||||||||
| 関連タイプ | isVersionOf | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | info:doi/10.1007/s00705-016-3023-4 | |||||||
| 権利 | ||||||||
| 権利情報 | The final publication is available at Springer via http://dx.doi.org/10.1007/s00705-016-3023-4 | |||||||
| フォーマット | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | application/pdf | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | AM | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||
| 日本十進分類法 | ||||||||
| 主題Scheme | NDC | |||||||
| 主題 | 488 | |||||||
