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Expression of Amphiregulin During the Pre- and Post-implantation Period in the Mouse Reproductive Tract
https://obihiro.repo.nii.ac.jp/records/383
https://obihiro.repo.nii.ac.jp/records/383550255e0-65b5-44be-b2e0-40792ce452aa
名前 / ファイル | ライセンス | アクション |
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expressionof.pdf (2.6 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-07-26 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Expression of Amphiregulin During the Pre- and Post-implantation Period in the Mouse Reproductive Tract | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Mice | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Implantation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Embryo transfer | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Amphiregulin | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | mRNA | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Lee, Dong-Soo
× Lee, Dong-Soo× Yanagimoto, Ueta Yoshiko× Suzuki, Hiroshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In mammals, embryo implantation is an essential step in reproduction. Implantation is a phenomenon that involves crosstalk between the blastocyst and the maternal endometrium. However, the molecular basis of the connections between the blastocyst and endometrium is not yet fully understood. Amphiregulin is a member of the epidermal growth factor family and is known to be expressed in the luminal epithelium of the mouse uterus on 3.5 days post coitum (dpc). Thus, to clarify the mechanism of amphiregulin at fetomaternal interface, we analyzed the expression pattern of amphiregulin mRNA in the oviducts and uteri of pregnant and psuedopregnant mice by means of real-time PCR. Amphiregulin expression in the pregnant uterus dramatically increased on 2.5 dpc, peaked on 3.5 dpc, and declined by 5.5 dpc. Furthermore, to analyze the effect of the presence of an embryo on amphiregulin expression, we determined the expression pattern of amphiregulin mRNA in the uterus after embryo transfer on 0.5 and 1.5 dpc. A previous study showed that the expression of amphiregulin mRNA depends on the concentration of progesterone. However, our present results indicate that amphiregulin mRNA is upregulated by the presence of fertilized eggs in the lumen of the oviduct on 0.5 dpc. | |||||
言語 | en | |||||
書誌情報 |
en : Journal of Reproduction and Development 巻 52, 号 6, p. 781-787, 発行日 2006 |
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出版者 | ||||||
言語 | en | |||||
出版者 | Japanese Society of Animal Reproduction | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 09168818 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10936678 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1262/jrd.18034 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | Japanese Society of Animal Reproduction | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |