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Expression of a Gene Encoding Trypanosoma congolense Putative Abc1 Family Protein is Developmentally Regulated(Parasitology)
名前 / ファイル | ライセンス | アクション |
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inoue67(2),157-164,2005.pdf (481.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||
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公開日 | 2015-09-29 | |||||||||||||||||||
タイトル | ||||||||||||||||||||
言語 | en | |||||||||||||||||||
タイトル | Expression of a Gene Encoding Trypanosoma congolense Putative Abc1 Family Protein is Developmentally Regulated(Parasitology) | |||||||||||||||||||
言語 | ||||||||||||||||||||
言語 | eng | |||||||||||||||||||
キーワード | ||||||||||||||||||||
言語 | en | |||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||
主題 | Trypanosoma congolense | |||||||||||||||||||
キーワード | ||||||||||||||||||||
言語 | en | |||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||
主題 | abc1 family protein | |||||||||||||||||||
キーワード | ||||||||||||||||||||
言語 | en | |||||||||||||||||||
主題Scheme | Other | |||||||||||||||||||
主題 | Coenzyme Q | |||||||||||||||||||
資源タイプ | ||||||||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||
資源タイプ | journal article | |||||||||||||||||||
著者 |
Baticados, Waren N.
× Baticados, Waren N.× Witola, William H.× 井上, 昇
WEKO
63
× Kim, Jung-yeon× Kuboki, Noritaka× 玄, 学南
WEKO
295
× 横山, 直明
WEKO
312
× Sugimoto, Chihiro
WEKO
252
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抄録 | ||||||||||||||||||||
内容記述タイプ | Abstract | |||||||||||||||||||
内容記述 | During the attempt to seek T. congolense species-specific diagnostic antigens, we discovered one cDNA clone (P74) encoding 74 kDa putative abc1 protein (p74) from T. congolense PCF cDNA library. It has been suggested that members of the abc1 family are novel chaperonins and essential for both the mitochondrial electron transfer in the bc 1 complex and the coenzyme Q biosynthesis. Although abc1 protein in yeast has a nuclear or mitochondrial subcellular location, neither nuclear localization signal nor mitochondrial targeting signal was found within p74. Northern blot analysis revealed that the transcription level of P74 mRNA in bloodstream form (BSF) cells were 4 times higher than that in procyclic form cells. Western blot analysis also indicated that p74 was only expressed in T. congolense BSF cells, and revealed that molecular mass of native p74 was not 74 kDa but 56 kDa. This indicates extensive post-translational modification in p74. Although further characterization of p74 will be required, our findings provide implications for CoQ biosynthesis pathway in T. congolense. | |||||||||||||||||||
書誌情報 |
en : Journal of Veterinary Medical Science 巻 67, 号 2, p. 157-164, 発行日 2005 |
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出版者 | ||||||||||||||||||||
出版者 | Japanese Society of Veterinary Science | |||||||||||||||||||
ISSN | ||||||||||||||||||||
収録物識別子タイプ | ISSN | |||||||||||||||||||
収録物識別子 | 09167250 | |||||||||||||||||||
書誌レコードID | ||||||||||||||||||||
収録物識別子タイプ | NCID | |||||||||||||||||||
収録物識別子 | AA10796138 | |||||||||||||||||||
DOI | ||||||||||||||||||||
関連タイプ | isIdenticalTo | |||||||||||||||||||
識別子タイプ | DOI | |||||||||||||||||||
関連識別子 | info:doi/10.1292/jvms.67.157 | |||||||||||||||||||
権利 | ||||||||||||||||||||
言語 | en | |||||||||||||||||||
権利情報 | Japanese Society of Veterinary Science | |||||||||||||||||||
フォーマット | ||||||||||||||||||||
内容記述タイプ | Other | |||||||||||||||||||
内容記述 | application/pdf | |||||||||||||||||||
著者版フラグ | ||||||||||||||||||||
出版タイプ | VoR | |||||||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |